ArticleBMC plant biology2014
Deletions of the SACPD-C locus elevate seed stearic acid levels but also result in fatty acid and morphological alterations in nitrogen fixing nodules.
Article in BMC plant biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 57 citations in OpenAlex.
- Sustainable industrial crop-based strategies for cocoa butter substitutes: advances in plant, microbial, and lipid engineering.Food chemistry: X · 2026Review
- Fatty Acid Desaturases GmROD1s Are Involved in Nodulation by Regulating the Flux of Polyunsaturated Fatty Acids.Plant, cell & environment · 2026Article
- A novel type of Brassica napus with higher stearic acid in seeds developed through genome editing of BnaSAD2 family.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Critical role for uricase and xanthine dehydrogenase in soybean nitrogen fixation and nodule development.The plant genome · 2023Article
- Soybean gene co-expression network analysis identifies two co-regulated gene modules associated with nodule formation and development.Molecular plant pathology · 2023Article
- Diversity of fatty acid biosynthesis genes across the soybean pangenome.The plant genome · 2023Article
- Bioengineering of Soybean Oil and Its Impact on Agronomic Traits.International journal of molecular sciences · 2023Review
- QTL Mapping of Palmitic Acid Content Using Specific-Locus Amplified Fragment Sequencing (SLAF-Seq) Genotyping in Soybeans (International journal of molecular sciences · 2022Article
- Progress in soybean functional genomics over the past decade.Plant biotechnology journal · 2022Review
- Transcriptomic Analysis Reveals the Regulatory Networks and Hub Genes Controlling the Unsaturated Fatty Acid Contents of Developing Seed in Soybean.Frontiers in plant science · 2022Article
- TILLING-by-SequencingInternational journal of molecular sciences · 2021Article
- Identification of SNP markers associated with soybean fatty acids contents by genome-wide association analyses.Molecular breeding : new strategies in plant improvement · 2021Article
- Improving soybean seed oil without poor agronomics.Journal of experimental botany · 2020Article
- Functional analysis and development of a CRISPR/Cas9 allelic series for a CPR5 ortholog necessary for proper growth of soybean trichomes.Scientific reports · 2019Article
- Molecular mapping and genomics of soybean seed protein: a review and perspective for the future.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2017Review
- Stearoyl-Acyl Carrier Protein Desaturase Mutations Uncover an Impact of Stearic Acid in Leaf and Nodule Structure.Plant physiology · 2017Article
- Identification of candidate genes from the SAD gene family in cotton for determination of cottonseed oil composition.Molecular genetics and genomics : MGG · 2017Article
- Genotyping-by-Sequencing-Based Investigation of the Genetic Architecture Responsible for a ∼Sevenfold Increase in Soybean Seed Stearic Acid.G3 (Bethesda, Md.) · 2017Article
- Fast neutron-induced structural rearrangements at a soybean NAP1 locus result in gnarled trichomes.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2016Article
- Targeted association mapping demonstrating the complex molecular genetics of fatty acid formation in soybean.BMC genomics · 2015Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSoybean (Glycine max) seeds are the primary source of edible oil in the United States. Despite its widespread utility, soybean oil is oxidatively unstable. Until recently, the majority of soybean oil underwent chemical hydrogenation, a process which also generates trans fats. An alternative to chemical hydrogenation is genetic modification of seed oil through identification and introgression of mutant alleles. One target for improvement is the elevation of a saturated fat with no negative cardiovascular impacts, stearic acid, which typically constitutes a minute portion of seed oil (~3%).
resultsWe examined radiation induced soybean mutants with moderately increased stearic acid (10-15% of seed oil, ~3-5 X the levels in wild-type soybean seeds) via comparative whole genome hybridization and genetic analysis. The deletion of one SACPD isoform encoding gene (SACPD-C) was perfectly correlated with moderate elevation of seed stearic acid content. However, SACPD-C deletion lines were also found to have altered nodule fatty acid composition and grossly altered morphology. Despite these defects, overall nodule accumulation and nitrogen fixation were unaffected, at least under laboratory conditions.
conclusionsAlthough no yield penalty has been reported for moderate elevated seed stearic acid content in soybean seeds, our results demonstrate that genetic alteration of seed traits can have unforeseen pleiotropic consequences. We have identified a role for fatty acid biosynthesis, and SACPD activity in particular, in the establishment and maintenance of symbiotic nitrogen fixation.
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