Evidence map›Paper›PMID 24886011›Full record

ArticleJournal of abnormal psychology2014

Anhedonia and the relative reward value of drug and nondrug reinforcers in cigarette smokers.

Adam M Leventhal, Michael Trujillo, Katherine J Ameringer, Jennifer W Tidey, Steve Sussman, Christopher W Kahler

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Journal of abnormal psychology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03326128 (High Dose Bupropion Treatment for Smoking Cessation - Pilot Study), which is not on this map. Cited by 43 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 3 pooled it
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03326128 phase2terminatednot on this mapstarted 2021, after this paper: background citation

High Dose Bupropion Treatment for Smoking Cessation - Pilot Study

TypeinterventionalSponsorUniversity of Southern CaliforniaRan2021 to 2023Enrolled12ConditionsSmoking Cessation, Smoking, Tobacco, Smoking (Tobacco) Addiction, Cessation, TobaccoArmsBupropion Hydrochloride
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 3 syntheses or guidelines pooled it, 58 citations in OpenAlex.

  1. Possible New Symptoms of Tobacco Withdrawal III: Reduced Positive Affect-A Review and Meta-analysis.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2021
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Pain characteristics and nicotine deprivation as predictors of performance during a laboratory paradigm of smoking cessation.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2020
    Trial
  6. Second Generation Electronic Nicotine Delivery System Vape Pen Exposure Generalizes as a Smoking Cue.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2018
    Trial
  7. Is the Effect of Anhedonia on Smoking Cessation Greater for Women Versus Men?Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2017
    Trial
  8. Trial
  9. Article
  10. Article
  11. Article
  12. Article
  13. Behavioral Economics and Tobacco Control: Current Practices and Future Opportunities.International journal of environmental research and public health · 2022
    Article
  14. Affect and subjective cognitive functioning by depression symptom levels during naturalistic cigarette smoking in premenopausal females who smoke daily.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2022
    Article
  15. Article
  16. Anhedonia in tobacco withdrawal among African-American smokers.Experimental and clinical psychopharmacology · 2021
    Article
  17. Article
  18. Gender Differences in Negative Affect During Acute Tobacco Abstinence Differ Between African American and White Adult Cigarette Smokers.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2019
    Article
  19. Anhedonia as a phenotypic marker of familial transmission of polysubstance use trajectories across midadolescence.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Adam M LeventhalDepartment of Preventive Medicine, University of Southern California Keck School of Medicine.
Michael TrujilloDepartment of Preventive Medicine, University of Southern California Keck School of Medicine.
Katherine J AmeringerDepartment of Preventive Medicine, University of Southern California Keck School of Medicine.
Jennifer W TideyCenter for Alcohol and Addiction Studies, Brown University School of Public Health.
Steve SussmanDepartment of Preventive Medicine, University of Southern California Keck School of Medicine.
Christopher W KahlerCenter for Alcohol and Addiction Studies, Brown University School of Public Health.
University of Southern California · USJohn Brown University · US

Funding

Training grant for Cancer Control and EpidemiologyT32CA009492 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PENTZ, MARY ANN · 1985 to 2019
$7.4M
Mechanisms Linking Anhedonia and Tobacco AddictionR01DA026831 · NIDA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI LEVENTHAL, ADAM MATTHEW · 2009 to 2012
$1.1M
Affective and Genetic Correlates of Amphetamine ResponseK08DA025041 · NIDA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI LEVENTHAL, ADAM MATTHEW · 2009 to 2013
$773k
NCI NIH HHS T32 CA009492NCI NIH HHS T32CA009492NIDA NIH HHS K08 DA025041NIDA NIH HHS K08-DA025041NIDA NIH HHS R01 DA026831NIDA NIH HHS R01-DA026831
6 · The paper itself

Abstract

Anhedonia-a psychopathologic trait indicative of diminished interest, pleasure, and enjoyment-has been linked to use of and addiction to several substances, including tobacco. We hypothesized that anhedonic drug users develop an imbalance in the relative reward value of drug versus nondrug reinforcers, which could maintain drug use behavior. To test this hypothesis, we examined whether anhedonia predicted the tendency to choose an immediate drug reward (i.e., smoking) over a less immediate nondrug reward (i.e., money) in a laboratory study of non-treatment-seeking adult cigarette smokers. Participants (N = 275, ≥10 cigarettes/day) attended a baseline visit that involved anhedonia assessment followed by 2 counterbalanced experimental visits: (a) after 16-hr smoking abstinence and (b) nonabstinent. At both experimental visits, participants completed self-report measures of mood state followed by a behavioral smoking task, which measured 2 aspects of the relative reward value of smoking versus money: (1) latency to initiate smoking when delaying smoking was monetarily rewarded and (2) willingness to purchase individual cigarettes. Results indicated that higher anhedonia predicted quicker smoking initiation and more cigarettes purchased. These relations were partially mediated by low positive and high negative mood states assessed immediately prior to the smoking task. Abstinence amplified the extent to which anhedonia predicted cigarette consumption among those who responded to the abstinence manipulation, but not the entire sample. Anhedonia may bias motivation toward smoking over alternative reinforcers, perhaps by giving rise to poor acute mood states. An imbalance in the reward value assigned to drug versus nondrug reinforcers may link anhedonia-related psychopathology to drug use.

Indexed as

Reinforcement, PsychologyAdultAnhedoniaFemaleHumansMaleMiddle AgedMotivationRewardSmoking

Identifiers

PMID24886011
PMCPMC4411231
OpenAlexW2333179986

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.