ArticleBMC complementary and alternative medicine2014
A study of antioxidant activity, enzymatic inhibition and in vitro toxicity of selected traditional Sudanese plants with anti-diabetic potential.
Article in BMC complementary and alternative medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
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- Integrated bioactivity assessment of Syzygium aromaticum bud extract from Sudan shows antimicrobial and antioxidant potential.Scientific reports · 2026Article
- Review
- High-pressure homogenization to improve the stability of liquid diabetes formula food for special medical purposes: Structural characteristics of caseinFood chemistry: X · 2024Article
- Article
- The Effect of Ionic Strength on the Formation and Stability of Ovalbumin-Xanthan Gum Complex Emulsions.Foods (Basel, Switzerland) · 2024Article
- Antimicrobial and Antioxidant Activities and Phytochemical Analysis ofInternational journal of microbiology · 2023Article
- Review
- Antidiabetic Potential of Medicinal Plants and Their Active Components.Biomolecules · 2019Review
- Evaluation of the Enzyme Inhibitory and Antioxidant Activities ofMolecules (Basel, Switzerland) · 2019Article
- In vitro toxicity determination of antifungal constituents from Combretum zeyheri.BMC complementary and alternative medicine · 2016Article
- In vitro antioxidant properties, free radicals scavenging activities of extracts and polyphenol composition of a non-timber forest product used as spice: Monodora myristica.Biological research · 2015Article
- Preconditioning L6 Muscle Cells with Naringin Ameliorates Oxidative Stress and Increases Glucose Uptake.PloS one · 2015Article
- Correlation of antiangiogenic, antioxidant and cytotoxic activities of some Sudanese medicinal plants with phenolic and flavonoid contents.BMC complementary and alternative medicine · 2014Article
- Herbal Drugs from Sudan: Traditional Uses and Phytoconstituents.Pharmacognosy reviewsReview
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5 authors.
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Abstract
backgroundDiabetes mellitus is a chronic metabolic disease with life-threatening complications. Despite the enormous progress in conventional medicine and pharmaceutical industry, herbal-based medicines are still a common practice for the treatment of diabetes. This study evaluated ethanolic and aqueous extracts of selected Sudanese plants that are traditionally used to treat diabetes.
methodsExtraction was carried out according to method described by Sukhdev et. al. and the extracts were tested for their glycogen phosphorylase inhibition, Brine shrimp lethality and antioxidant activity using (DPPH) radical scavenging activity and iron chelating activity. Extracts prepared from the leaves of Ambrosia maritima, fruits of Foeniculum vulgare and Ammi visnaga, exudates of Acacia Senegal, and seeds of Sesamum indicum and Nigella sativa.
resultsNigella sativa ethanolic extract showed no toxicity on Brine shrimp Lethality Test, while its aqueous extract was toxic. All other extracts were highly toxic and ethanolic extracts of Foeniculum vulgare exhibited the highest toxicity. All plant extracts with exception of Acacia senegal revealed significant antioxidant activity in DPPH free radical scavenging assay.
conclusionsThese results highly agree with the ethnobotanical uses of these plants as antidiabetic. This study endorses further studies on plants investigated, to determine their potential for type 2 diabetes management. Moreover isolation and identification of active compounds are highly recommended.
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