ArticleBMC psychiatry2014
The relationship between neurocognition and symptomatology in people with schizophrenia: social cognition as the mediator.
Article in BMC psychiatry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 66 citations in OpenAlex.
- Assessing social cognition in patients with schizophrenia and healthy controls using the reading the mind in the eyes test (RMET): a systematic review and meta-regression.Psychological medicine · 2024Pooled it
- Disentangling the Relationships Between the Clinical Symptoms of Schizophrenia Spectrum Disorders and Theory of Mind: A Meta-analysis.Schizophrenia bulletin · 2023Pooled it
- Genome-wide meta-analysis of cognitive empathy: heritability, and correlates with sex, neuropsychiatric conditions and cognition.Molecular psychiatry · 2018Pooled it
- Decline in Working Memory in Stable Schizophrenia May Be Related to Attentional Impairment: Mediating Effects of Negative Symptoms, a Cross-Sectional Study.Neuropsychiatric disease and treatment · 2024Trial
- Event-related potential correlates of ESS-C-defined relapse-risk status in clinically stable patients with schizophrenia: a cross-sectional study.BMC psychiatry · 2026Article
- Cognitive presentation at psychosis onset through premorbid deterioration and exposure to environmental risk factors.Psychological medicine · 2025Article
- Association of empathy with clinical symptoms and cognitive function in chronic schizophrenia patients with and without suicide attempts.European archives of psychiatry and clinical neuroscience · 2024Article
- Loss of empathy in stroke.Frontiers in psychology · 2024Article
- Enhanced computerized cognitive remediation therapy improved cognitive function, negative symptoms, and GDNF in male long-term inpatients with schizophrenia.Frontiers in psychiatry · 2024Article
- Interplay among positive and negative symptoms, neurocognition, social cognition, and functioning in clinically stable patients with schizophrenia: a network analysis.F1000Research · 2021Article
- Association of Negative Symptoms of Schizophrenia Assessed by the BNSS and SNS Scales With Neuropsychological Performance: A Gender Effect.Frontiers in psychiatry · 2021Article
- Caregivers' Grit Moderates the Relationship Between Children's Executive Function and Aggression.Frontiers in psychology · 2020Article
- Social vs. non-social measures of learning potential for predicting community functioning across phase of illness in schizophrenia.Schizophrenia research · 2019Article
- What Do You Have in Mind? Measures to Assess Mental State Reasoning in Neuropsychiatric Populations.Frontiers in psychiatry · 2019Review
- Neurocognitive and theory of mind deficits and poor social competence in schizophrenia: The moderating role of social disinterest attitudes.Psychiatry research · 2018Article
- The relationship between clinical insight and cognitive and affective empathy in schizophrenia.Schizophrenia research. Cognition · 2018Article
- An evaluation of functional mental capacity in forensic mental health practice: the Dundrum capacity ladders validation study.BMC psychiatry · 2018Article
- Cognitive dysfunction and negative symptoms in patients with schizophrenia and their first-degree relatives from simplex and multiplex families.Neuropsychiatric disease and treatment · 2018Article
- Social Cognition, Executive Functions and Self-Report of Psychological Distress in Huntington's Disease.PLoS currents · 2016Article
- Effect of theory of mind and peer victimization on the schizotypy-aggression relationship.NPJ schizophrenia · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe relationship between neurocognition and symptomatology in people with schizophrenia has been established. The present study examined whether social cognition could mediate this relationship.
methodsThere were 119 participants (58 people with paranoid schizophrenia and 61 healthy controls) participated in this study. Neurocognition was assessed by Raven's Progressive Matrices Test, the Judgment of Line Orientation Test, and the Tower of London Test. Psychiatric symptoms in people with schizophrenia were assessed by the Positive and Negative Syndrome Scale. Social cognition was measured by the Faux Pas Test, the "Reading the Mind in the Eyes" Test, and the Interpersonal Reactivity Index.
resultsResults were consistent with previous findings that neurocognition and social cognition were impaired in the clinical participants. A novel observation is that social cognition significantly mediated the relationship between neurocognition and symptomatology.
conclusionsThese findings suggest that neurocognitive deficits predispose people with schizophrenia to worse psychiatric symptoms through the impairment of social cognition. Findings of the present study provide important insight into a functional model of schizophrenia that could guide the development of cost-effective interventions for people with schizophrenia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.