Evidence map›Paper›PMID 24885146›Full record

GuidelineTrials2014

Effectiveness guidance document (EGD) for Chinese medicine trials: a consensus document.

Claudia M Witt, Mikel Aickin, Daniel Cherkin, Chun Tao Che, Charles Elder, Andrew Flower, Richard Hammerschlag, Jian-Ping Liu, Lixing Lao, Steve Phurrough and 9 more

Abstract readConsensus StatementPractice GuidelineReview
In one paragraph

Guideline in Trials, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Claudia M WittInstitute for Complementary and Integrative Medicine, University Hospital Zurich, Zurich, Switzerland. claudia.witt@uzh.ch.
Mikel Aickin
Daniel Cherkin
Chun Tao Che
Charles Elder
Andrew Flower
Richard Hammerschlag
Jian-Ping Liu
Lixing Lao
Steve Phurrough
Cheryl Ritenbaugh
Lee Hullender Rubin
Rosa Schnyer
Peter M Wayne
Shelly Rafferty Withers
Bian Zhao-Xiang
Jeanette Young
Brian M Berman
Collaborators

Funding

Department of Health PDF-2011-04-027
6 · The paper itself

Abstract

backgroundThere is a need for more Comparative Effectiveness Research (CER) on Chinese medicine (CM) to inform clinical and policy decision-making. This document aims to provide consensus advice for the design of CER trials on CM for researchers. It broadly aims to ensure more adequate design and optimal use of resources in generating evidence for CM to inform stakeholder decision-making.

methodsThe Effectiveness Guidance Document (EGD) development was based on multiple consensus procedures (survey, written Delphi rounds, interactive consensus workshop, international expert review). To balance aspects of internal and external validity, multiple stakeholders, including patients, clinicians, researchers and payers were involved in creating this document.

resultsRecommendations were developed for "using available data" and "future clinical studies". The recommendations for future trials focus on randomized trials and cover the following areas: designing CER studies, treatments, expertise and setting, outcomes, study design and statistical analyses, economic evaluation, and publication.

conclusionThe present EGD provides the first systematic methodological guidance for future CER trials on CM and can be applied to single or multi-component treatments. While CONSORT statements provide guidelines for reporting studies, EGDs provide recommendations for the design of future studies and can contribute to a more strategic use of limited research resources, as well as greater consistency in trial design.

Indexed as

Clinical Trials as TopicComparative Effectiveness ResearchConsensusDelphi TechniqueHumansMedicine, Chinese TraditionalResearch Design

Identifiers

PMID24885146
PMCPMC4045891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.