ArticleBMC evolutionary biology2014
The history of the North African mitochondrial DNA haplogroup U6 gene flow into the African, Eurasian and American continents.
Article in BMC evolutionary biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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30 citing papers in PubMed.
- Integrating genetic, historical, and demographic evidence to reconstruct Argentina's matrilineal ancestry.Human genetics · 2026Article
- The North African maternal genetic diversity enriched by historical migrations: insights from a comprehensive analysis of complete mitogenomes.Mammalian genome : official journal of the International Mammalian Genome Society · 2026Article
- Uniparental analysis of Deep Maniot Greeks reveals genetic continuity from the pre-Medieval era.Communications biology · 2026Article
- Article
- Humanin P3S, haplogroup N1b and the risk of Alzheimer's disease.Aging cell · 2024Article
- New Canary Islands Roman mediated settlement hypothesis deduced from coalescence ages of curated maternal indigenous lineages.Scientific reports · 2024Article
- Chronological and genetic analysis of an Upper Palaeolithic female infant burial from Borsuka Cave, Poland.iScience · 2023Article
- Whole mitogenomes reveal that NW Africa has acted both as a source and a destination for multiple human movements.Scientific reports · 2023Article
- Digging into the admixture strata of current-day Canary Islanders based on mitogenomes.iScience · 2023Article
- The relevance of late MSA mandibles on the emergence of modern morphology in Northern Africa.Scientific reports · 2022Article
- Exploring statistical weight estimates for mitochondrial DNA matches involving heteroplasmy.International journal of legal medicine · 2022Article
- Biomolecular insights into North African-related ancestry, mobility and diet in eleventh-century Al-Andalus.Scientific reports · 2021Article
- Environmental factors modulated ancient mitochondrial DNA variability and the prevalence of rheumatic diseases in the Basque Country.Scientific reports · 2019Article
- Dissecting human North African gene-flow into its western coastal surroundings.Proceedings. Biological sciences · 2019Article
- Mitochondrial DNA control region diversity in a population from Parana state-increasing the Brazilian forensic database.International journal of legal medicine · 2019Article
- Mitogenomes illuminate the origin and migration patterns of the indigenous people of the Canary Islands.PloS one · 2019Article
- Ancient genomes from North Africa evidence prehistoric migrations to the Maghreb from both the Levant and Europe.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Carriers of mitochondrial DNA macrohaplogroup L3 basal lineages migrated back to Africa from Asia around 70,000 years ago.BMC evolutionary biology · 2018Article
- Pseudogenization of theZoological research · 2017Article
- Carriers of mitochondrial DNA macrohaplogroup R colonized Eurasia and Australasia from a southeast Asia core area.BMC evolutionary biology · 2017Article
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7 authors.
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Abstract
backgroundComplete mitochondrial DNA (mtDNA) genome analyses have greatly improved the phylogeny and phylogeography of human mtDNA. Human mitochondrial DNA haplogroup U6 has been considered as a molecular signal of a Paleolithic return to North Africa of modern humans from southwestern Asia.
resultsUsing 230 complete sequences we have refined the U6 phylogeny, and improved the phylogeographic information by the analysis of 761 partial sequences. This approach provides chronological limits for its arrival to Africa, followed by its spreads there according to climatic fluctuations, and its secondary prehistoric and historic migrations out of Africa colonizing Europe, the Canary Islands and the American Continent.
conclusionsThe U6 expansions and contractions inside Africa faithfully reflect the climatic fluctuations that occurred in this Continent affecting also the Canary Islands. Mediterranean contacts drove these lineages to Europe, at least since the Neolithic. In turn, the European colonization brought different U6 lineages throughout the American Continent leaving the specific sign of the colonizers origin.
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