ArticleActa veterinaria Scandinavica2014
Exogenous estradiol improves shell strength in laying hens at the end of the laying period.
Article in Acta veterinaria Scandinavica, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 32 citations in OpenAlex.
- Influence of Dietary Probiotic and Alpha-Monolaurin on Performance, Egg Quality, Blood Constituents, and Egg Fatty Acids' Profile in Laying Hens.Probiotics and antimicrobial proteins · 2024Article
- Supplementation of the Combination of Quercetin and Vitamin E Alleviates the Effects of Heat Stress on the Uterine Function and Hormone Synthesis in Laying Hens.Animals : an open access journal from MDPI · 2024Article
- Effects of dietary organic acids and probiotics on laying performance, egg quality, serum antioxidants and expressions of reproductive genes of laying ducks in the late phase of production.Poultry science · 2022Article
- Naringin prevents follicular atresia by inhibiting oxidative stress in the aging chicken.Poultry science · 2022Article
- Sodium humate alters the intestinal microbiome, short-chain fatty acids, eggshell ultrastructure, and egg performance of old laying hens.Frontiers in veterinary science · 2022Article
- Molting method alternative and detection of estrogen receptors by immunohistochemical methods on molted layers.Tropical animal health and production · 2021Article
- Improvement of eggshell quality by dietary N-carbamylglutamate supplementation in laying chickens.Poultry science · 2020Article
- A model of pre-pubertal broiler breeder estradiol-17β levels predicts advanced sexual maturation for birds with high body weight or short juvenile day-length exposure.Poultry science · 2019Article
- The differences of gonadal hormones and uterine transcriptome during shell calcification of hens laying hard or weak-shelled eggs.BMC genomics · 2019Article
- Melatonin implantation improved the egg-laying rate and quality in hens past their peak egg-laying age.Scientific reports · 2016Article
- Estrogenic contamination by manure fertilizer in organic farming: a case study with the lizard Podarcis sicula.Ecotoxicology (London, England) · 2016Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCracked shells, due to age related reduction of shell quality, are a costly problem for the industry. Parallel to reduced shell quality the skeleton becomes brittle resulting in bone fractures. Calcium, a main prerequisite for both eggshell and bone, is regulated by estrogen in a complex manner. The effects of estrogen, given in a low continuous dose, were studied regarding factors involved in age related changes in shell quality and bone strength of laying hens. A pellet containing 0.385 mg estradiol 3-benzoate (21-day-release) or placebo was inserted subcutaneously in 20 birds each of Lohmann Selected Leghorn (LSL) and Lohmann Brown (LB) at 70 weeks of age. Eggs were collected before and during the experiment for shell quality measurements. Blood samples for analysis of total calcium were taken three days after the insertion and at sacrifice (72 weeks). Right femur was used for bone strength measurements and tissue samples from duodenum and shell gland were processed for morphology, immunohistochemical localization of estrogen receptors (ERα, ERβ), plasma membrane calcium ATPase (PMCA) and histochemical localization of carbonic anhydrase (CA).
resultsEstrogen treatment increased shell thickness of both hybrids. In addition, shell weight and shell deformation improved in eggs from the brown hybrids. The more pronounced effect on eggs from the brown hybrid may be due to a change in sensitivity to estrogen, especially in surface epithelial cells of the shell gland, shown as an altered ratio between ERα and ERβ. A regulatory effect of estrogen on CA activity, but not PMCA, was seen in both duodenum and shell gland, and a possible connection to shell quality is discussed. Bone strength was unaffected by treatment, but femur was stronger in LSL birds suggesting that the hybrids differ in calcium allocation between shell and bone at the end of the laying period. Plasma calcium concentrations and egg production were unaffected.
conclusionsA low continuous dose of estrogen improves shell strength but not bone strength in laying hens at the end of the laying period.
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