ArticleBMC neurology2014
Social participation in patients with multiple sclerosis: correlations between disability and economic burden.
Article in BMC neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed.
- Environmental influences on community participation among people with multiple sclerosis: A mixed methods study.PloS one · 2026Article
- Navigating social roles: Exploring the impact of disability-related stress on minority individuals with multiple sclerosis.Multiple sclerosis and related disorders · 2025Article
- Exploring Perceptions of Physical Activity in Individuals Newly Diagnosed with Multiple Sclerosis.Journal of clinical medicine · 2025Article
- Perceived and physiological strains of societal participation in people with multiple sclerosis: a real-time assessment study.Journal of rehabilitation medicine · 2024Observational
- Perceptions of Therapeutic Climbing for Patients with Multiple Sclerosis in Neurorehabilitation: A Qualitative Study.Healthcare (Basel, Switzerland) · 2024Article
- Article
- A step toward restoring hand functions in patients with multiple sclerosis-a study protocol.Frontiers in rehabilitation sciences · 2023Article
- Pet Ownership and Multiple Sclerosis during COVID-19.International journal of environmental research and public health · 2021Article
- Secondary health conditions and social role satisfaction in adults with long-term physical disability.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2019Article
- Influence of Cognitive and Motor Abilities on the Level of Current Functioning in People with Multiple Sclerosis.Zdravstveno varstvo · 2019Article
- The role of appraisal and coping style in relation with societal participation in fatigued patients with multiple sclerosis: a cross-sectional multiple mediator analysis.Journal of behavioral medicine · 2016Article
- Quantifying the relationship between increased disability and health care resource utilization, quality of life, work productivity, health care costs in patients with multiple sclerosis in the US.BMC health services research · 2016Article
- Self-reported quality of life in multiple sclerosis patients: preliminary results based on the Polish MS Registry.Patient preference and adherence · 2016Article
- Satisfaction with alemtuzumab in relapsing multiple sclerosis patients: Results from the real-world PRO-ACT study.Multiple sclerosis journal - experimental, translational and clinicalArticle
- Costs and quality of life by disability among people with multiple sclerosis: a register-based study in Sweden.Multiple sclerosis journal - experimental, translational and clinicalArticle
- Fatigue, Sleep Quality, and Disability in Relation to Quality of Life in Multiple Sclerosis.International journal of MS careArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEconomic costs related to treatment of multiple sclerosis (MS) must be justified by health state, quality of life (QOL) and social participation improvement. This study aims to describe correlations between social participation, economic costs, utility and MS-specific QOL in a sample of patients with MS (pwMS).
methodsWe interviewed 42 pwMS receiving natalizumab and collected clinical data, direct medical costs, productivity loss, utility (EQ5D-VAS), MS-specific QOL (SEP-59), social participation with the Impact on Participation and Autonomy questionnaire (IPA). We performed descriptive and correlation analyses.
results41 pwMS, with a mean Expanded Disability Status Scale (EDSS) score of 4.0, completed questionnaires. Mean annual global cost per patient was 68448 +/-33374 Euros and increased with EDSS (r = 0.644), utility (r = -0.456) and IPA (r = 0.519-0.671) worsening. Mean utility was 0.52 +/- 0.28. Correlations between IPA and QOL (EQ5D-VAS or SEP-59) were observed (r = -0.53 to -0.78). Association between QOL and EDSS was smaller (EQ5D-VAS) or absent. Productivity losses were poorly correlated to EDSS (r = 0.375).
conclusionModerate to strong correlations of social participation with clinical status (EDSS), QOL, utility and economic costs encourage exploring better these links in larger cohorts. The stronger correlation between social participation and QOL than between EDSS and QOL needs to be confirmed.
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