ArticleBMC cancer2014
Changes in vitamin and mineral supplement use after breast cancer diagnosis in the Pathways Study: a prospective cohort study.
Article in BMC cancer, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06137833 (Clinical Study on Wide Spectrum Micronutrients Supplementation in Patients With Cancer Related Fatigue During Neoadjuvant and Adjuvant Chemotherapy), which is not on this map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical Study on Wide Spectrum Micronutrients Supplementation in Patients With Cancer Related Fatigue During Neoadjuvant and Adjuvant Chemotherapy
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Clinical practice guidelines on the evidence-based use of integrative therapies during and after breast cancer treatment.CA: a cancer journal for clinicians · 2017Guideline
- Clinical practice guidelines on the use of integrative therapies as supportive care in patients treated for breast cancer.Journal of the National Cancer Institute. Monographs · 2014Guideline
- Dietary supplement intake in women with breast cancer before and after diagnosis: results from the SUCCESS C trial.BMC cancer · 2024Trial
- A randomized, placebo-controlled trial of diindolylmethane for breast cancer biomarker modulation in patients taking tamoxifen.Breast cancer research and treatment · 2017Trial
- Vitamin/mineral and non-vitamin/non-mineral supplement use of breast cancer survivors in Korea.Nutrition research and practice · 2026Article
- Diet and Breast Cancer Survivorship: A Scoping Review.Journal of breast cancer · 2026Review
- Dietary Responses to Non-Communicable Chronic Disease Diagnoses-A Scoping Review.International journal of general medicine · 2026Review
- Dietary Supplement Use in Women Diagnosed with Breast Cancer.The Journal of nutrition · 2023Article
- The Self-Administered Use of Complementary and Alternative Medicine (CAM) Supplements and Antioxidants in Cancer Therapy and the Critical Role of Nrf-2-A Systematic Review.Antioxidants (Basel, Switzerland) · 2022Review
- Article
- Do cancer survivors change their diet after cancer diagnosis?Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Article
- Changes in Eating Habits in Breast Cancer Patients.Zdravstveno varstvo · 2020Article
- Dietary supplement use among cancer survivors and the general population: a nation-wide cross-sectional study.BMC cancer · 2017Article
- BMI, Lifestyle Factors and Taxane-Induced Neuropathy in Breast Cancer Patients: The Pathways Study.Journal of the National Cancer Institute · 2017Article
- Phytotherapy and Nutritional Supplements on Breast Cancer.BioMed research international · 2017Review
- Use of complementary and alternative medicine and breast cancer survival in the Health, Eating, Activity, and Lifestyle Study.Breast cancer research and treatment · 2016Article
- Complementary and alternative medicine use among US cancer survivors.Journal of cancer survivorship : research and practice · 2016Article
- Association Between Complementary and Alternative Medicine Use and Breast Cancer Chemotherapy Initiation: The Breast Cancer Quality of Care (BQUAL) Study.JAMA oncology · 2016Article
- "I Made All Decisions Myself": Breast Cancer Treatment Decision-Making by Receivers and Decliners.Asia-Pacific journal of oncology nursingArticle
Corrections and comments
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Authors and funding
12 authors at 6 institutions in 1 country.
Funding
Abstract
backgroundVitamin and mineral supplement use after a breast cancer diagnosis is common and controversial. Dosages used and the timing of initiation and/or discontinuation of supplements have not been clearly described.
methodsWe prospectively examined changes in use of 17 vitamin/mineral supplements in the first six months following breast cancer diagnosis among 2,596 members (28% non-white) of Kaiser Permanente Northern California. We used multivariable logistic regression to examine demographic, clinical, and lifestyle predictors of initiation and discontinuation.
resultsMost women used vitamin/mineral supplements before (84%) and after (82%) diagnosis, with average doses far in excess of Institute of Medicine reference intakes. Over half (60.2%) reported initiating a vitamin/mineral following diagnosis, 46.3% discontinuing a vitamin/mineral, 65.6% using a vitamin/mineral continuously, and only 7.2% not using any vitamin/mineral supplement before or after diagnosis. The most commonly initiated supplements were calcium (38.2%), vitamin D (32.01%), vitamin B6 (12.3%) and magnesium (11.31%); the most commonly discontinued supplements were multivitamins (17.14%), vitamin C (15.97%) and vitamin E (45.62%). Higher education, higher intake of fruits/vegetables, and receipt of chemotherapy were associated with initiation (p-values <0.05). Younger age and breast-conserving surgery were associated with discontinuation (p-values <0.05).
conclusionsIn this large cohort of ethnically diverse breast cancer patients, high numbers of women used vitamin/mineral supplements in the 6 months following breast cancer diagnosis, often at high doses and in combination with other supplements. The immediate period after diagnosis is a critical time for clinicians to counsel women on supplement use.
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