Evidence map›Paper›PMID 24884500›Full record

ArticleMalaria journal2014

Screening for adulticidal activity against Anopheles arabiensis in ten plants used as mosquito repellent in South Africa.

Edison J Mavundza, Rajendra Maharaj, Jude C Chukwujekwu, Jeffrey F Finnie, Johannes Van Staden

Open access · goldAbstract read
In one paragraph

Article in Malaria journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 29 citations in OpenAlex.

  1. Molecules (Basel, Switzerland) · 2026
    Review
  2. Evaluation of larvicidal potential of Eritrean medicinal plants againstJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024
    Article
  3. Article
  4. Article
  5. Larvicidal activity ofJournal of experimental pharmacology · 2019
    Article
  6. Article
  7. Evidence-based complementary and alternative medicine : eCAM · 2017
    Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Edison J MavundzaMalaria Research Unit, Medical Research Council, 491 Peter Mokaba Ridge, Overport, Durban 4001, South Africa. edison.mavundza@mrc.ac.za.
Rajendra Maharaj
Jude C Chukwujekwu
Jeffrey F Finnie
Johannes Van Staden
University of KwaZulu-Natal · ZASouth African Medical Research Council · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDue to the development of resistance to synthetic insecticides, adverse effects to human health, non-target organisms and the environment, there is an urgent need to develop new insecticides, which are effective, safe, biodegrable and target-specific. This study was undertaken to evaluate the adulticidal activity of 10 plants used traditionally as mosquito repellents in South Africa.

methodsThe dried plant materials were extracted with dichloromethane (DCM) and ethanol (EtOH). The extracts were evaluated for adulticidal activity against Anopheles arabiensis mosquitoes, a potent malaria vector in South Africa. Adult mortality was observed after 24 hours of exposure.

resultsAll the extracts showed adulticidal activity. The highest activity was observed in both DCM and EtOH extracts of Aloe ferox leaves with 98 and 86% mosquito mortality, respectively. The DCM extract of A. ferox leaves was then subjected to a dose-dependent bioassay to determine the EC50 value. The extract exhibited an EC50 value of 4.92 mg/ml.

conclusionThe results of the present study showed that the DCM extract of A. ferox leaves may have the potential to be used as an insecticide against An. arabiensis. Further studies to isolate and identify active compounds are in progress.

Indexed as

AloeAnimalsAnophelesBiological AssayFemaleInsecticidesPlant ExtractsPlant LeavesSouth AfricaSurvival AnalysisInsecticidesPlant Extracts

Identifiers

PMID24884500
PMCPMC4016781
OpenAlexW2111087194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.