ArticleBMC genomics2014
RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters.
Article in BMC genomics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.
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Who cites it
66 citing papers in PubMed, 149 citations in OpenAlex.
- Investigating the bHLH transcription factor TSARL1 as marker and regulator of saponin biosynthesis in Chenopodium quinoa.Journal of the science of food and agriculture · 2025Article
- Metabolic Engineering of Terpenoid Biosynthesis in Medicinal Plants: From Genomic Insights to Biotechnological Applications.Current issues in molecular biology · 2025Review
- Glandless, a tomato HD-ZIP transcription factor, is important for the gland formation of type VI trichomes.The Plant journal : for cell and molecular biology · 2025Article
- Biosynthesis of Camphane Volatile Terpenes inPlants (Basel, Switzerland) · 2025Article
- Review
- A plant virus manipulates both its host plant and the insect that facilitates its transmission.Science advances · 2025Article
- Transcriptomic and Phenotypic Responses of Cucumber Trichome Density to Silver Nitrate and Sodium Thiosulfate Application.International journal of molecular sciences · 2025Article
- Transcriptome analysis ofFrontiers in plant science · 2025Article
- Whole-genome identification and functional analysis of grape bHLH transcription factors: new insights into the regulation of monoterpene biosynthesis.Frontiers in plant science · 2025Article
- The Mitochondrial Blueprint: Unlocking Secondary Metabolite Production.Metabolites · 2024Review
- AInternational journal of molecular sciences · 2024Article
- Gas Chromatography-Mass Spectrometry Metabolites and Transcriptome Profiling Reveal Molecular Mechanisms and Differences in Terpene Biosynthesis in TwoInternational journal of molecular sciences · 2024Article
- WRKY Transcription Factors inBiomolecules · 2023Article
- Article
- Advances in the Research on Plant WRKY Transcription Factors Responsive to External Stresses.Current issues in molecular biology · 2023Review
- Methyl Jasmonate- and Salicylic Acid-Induced Transcription FactorInternational journal of molecular sciences · 2023Article
- Article
- Integrated Transcriptomic, Metabolomic, and Physiological Analyses Reveal New Insights into Fragrance Formation in the Heartwood ofInternational journal of molecular sciences · 2022Article
- Integrative analysis of the steroidal alkaloids distribution and biosynthesis of bulbs Fritillariae Cirrhosae through metabolome and transcriptome analyses.BMC genomics · 2022Article
- ODORANT1 targets multiple metabolic networks in petunia flowers.The Plant journal : for cell and molecular biology · 2022Article
6 more citing papers are in PubMed but not listed here.
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGlandular trichomes are production and storage organs of specialized metabolites such as terpenes, which play a role in the plant's defense system. The present study aimed to shed light on the regulation of terpene biosynthesis in Solanum lycopersicum trichomes by identification of transcription factors (TFs) that control the expression of terpene synthases.
resultsA trichome transcriptome database was created with a total of 27,195 contigs that contained 743 annotated TFs. Furthermore a quantitative expression database was obtained of jasmonic acid-treated trichomes. Sixteen candidate TFs were selected for further analysis. One TF of the MYC bHLH class and one of the WRKY class were able to transiently transactivate S. lycopersicum terpene synthase promoters in Nicotiana benthamiana leaves. Strikingly, SlMYC1 was shown to act synergistically with a previously identified zinc finger-like TF, Expression of Terpenoids 1 (SlEOT1) in transactivating the SlTPS5 promoter.
conclusionsHigh-throughput sequencing of tomato stem trichomes led to the discovery of two transcription factors that activated several terpene synthase promoters. Our results identified new elements of the transcriptional regulation of tomato terpene biosynthesis in trichomes, a largely unexplored field.
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