SynthesisBioMed research international2014
Biodegradable polyphosphazene biomaterials for tissue engineering and delivery of therapeutics.
Synthesis in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Polyphosphazene-Based Nanotherapeutics.Journal of functional biomaterials · 2025Review
- Biodegradable Conducting Polymer-Based Composites for Biomedical Applications-A Review.Polymers · 2024Review
- Novel Approaches to the Establishment of Local Microenvironment from Resorbable Biomaterials in the Brain In Vitro Models.International journal of molecular sciences · 2023Review
- Cyclo- and Polyphosphazenes for Biomedical Applications.Molecules (Basel, Switzerland) · 2022Review
- Article
- Biodegradable Polyphosphazenes for Regenerative Engineering.Journal of materials research · 2022Article
- In Situ Hydrogels for Effective Treatment of Cancer: Strategies and Polymers Used.Recent advances in drug delivery and formulation · 2022Article
- Synthesis and Characterization of Macroinitiators Based on Polyorganophosphazenes for the Ring Opening Polymerization ofPolymers · 2021Article
- Berberine-releasing electrospun scaffold induces osteogenic differentiation of DPSCs and accelerates bone repair.Scientific reports · 2021Article
- Biomedical applications of polyphosphazenes.Medical devices & sensors · 2020Article
- The Thermal Properties and Degradability of Chiral Polyester-Imides Based on Several l/d-Amino Acids.Polymers · 2020Article
- Polyphosphazene polymers: The next generation of biomaterials for regenerative engineering and therapeutic drug delivery.Journal of vacuum science and technology. B, Nanotechnology & microelectronics : materials, processing, measurement, & phenomena : JVST B · 2020Review
- Generational Biodegradable and Regenerative Polyphosphazene Polymers and their Blends with Poly (lactic-co-glycolic acid).Progress in polymer science · 2019Article
- Injectable Hydrogels for Cancer Therapy over the Last Decade.Pharmaceutics · 2019Review
- Synthesis, Physicochemical Analysis, and Side Group Optimization of Degradable Dipeptide-Based Polyphosphazenes as Potential Regenerative Biomaterials.ACS applied polymer materials · 2019Article
- Biodegradable Materials and Metallic Implants-A Review.Journal of functional biomaterials · 2017Review
- Review
- Biodegradable Polyphosphazene-Based Blends for Regenerative Engineering.Regenerative engineering and translational medicine · 2017Article
- A Highly Hydrophilic and Biodegradable Novel Poly(amide-imide) for Biomedical Applications.Polymers · 2016Article
- Vascularization of three-dimensional engineered tissues for regenerative medicine applications.Acta biomaterialia · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Degradable biomaterials continue to play a major role in tissue engineering and regenerative medicine as well as for delivering therapeutic agents. Although the chemistry of polyphosphazenes has been studied extensively, a systematic review of their applications for a wide range of biomedical applications is lacking. Polyphosphazenes are synthesized through a relatively well-known two-step reaction scheme which involves the substitution of the initial linear precursor with a wide range of nucleophiles. The ease of substitution has led to the development of a broad class of materials that have been studied for numerous biomedical applications including as scaffold materials for tissue engineering and regenerative medicine. The objective of this review is to discuss the suitability of poly(amino acid ester)phosphazene biomaterials in regard to their unique stimuli responsive properties, tunable degradation rates and mechanical properties, as well as in vitro and in vivo biocompatibility. The application of these materials in areas such as tissue engineering and drug delivery is discussed systematically. Lastly, the utility of polyphosphazenes is further extended as they are being employed in blend materials for new applications and as another method of tailoring material properties.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.