ArticleAdvances in bioscience and biotechnology (Print)2013
LL-37 induced cystitis and the receptor for advanced glycation end-products (RAGE) pathway.
Article in Advances in bioscience and biotechnology (Print), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 16 citations in OpenAlex.
- Elucidating the Urothelial-Dependent and -Independent Mechanisms Involved in the Mouse Bladder Contractility Alterations by Acute Methylglyoxal Exposure.Biomedicines · 2026Article
- Article
- Enhanced RAGE Expression and Excess Reactive-Oxygen Species Production Mediates Rho Kinase-Dependent Detrusor Overactivity After Methylglyoxal Exposure.Frontiers in physiology · 2022Article
- IL-33 mast cell axis is central in LL-37 induced bladder inflammation and pain in a murine interstitial cystitis model.Cytokine · 2018Article
- Disulfide high mobility group box-1 causes bladder pain through bladder Toll-like receptor 4.BMC physiology · 2017Article
- Bladder pain in an LL-37 interstitial cystitis and painful bladder syndrome model.American journal of clinical and experimental urology · 2017Article
- Protease-Activated Receptor 4 Induces Bladder Pain through High Mobility Group Box-1.PloS one · 2016Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
To elucidate pathways in bladder inflammation, we employed our physiologically relevant LL-37 induced cystitis model. Based on inflammatory studies involving other organ systems implicating the receptor for advanced glycation end-products (RAGE), we first hypothesized that RAGE is critically involved in LL-37 induced cystitis. We further hypothesized a common RAGE ligand - high mobility group box 1 (HMGB1) is up-regulated in bladders challenged with LL-37. Finally, we hypothesized NF-
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Registered trials
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