Evidence map›Paper›PMID 24883173›Full record

ArticleThe American journal of case reports2014

The forgotten disease: Bilateral lemierre's disease with mycotic aneurysm of the vertebral artery.

Tanush Gupta, Kaushal Parikh, Sonam Puri, Sahil Agrawal, Nikhil Agrawal, Divakar Sharma, Lawrence DeLorenzo

Abstract read
In one paragraph

Article in The American journal of case reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

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  6. Case reports in infectious diseases · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Tanush GuptaDepartment of Internal Medicine, Westchester Medical Center, New York Medical College, Valhalla, NY, U.S.A.
Kaushal ParikhDepartment of Internal Medicine, Westchester Medical Center, New York Medical College, Valhalla, NY, U.S.A.
Sonam PuriDepartment of Internal Medicine, University of Connecticut, Farmington, CT, U.S.A.
Sahil AgrawalDepartment of Internal Medicine, Westchester Medical Center, New York Medical College, Valhalla, NY, U.S.A.
Nikhil AgrawalDepartment of Internal Medicine, University of Florida, Gainesville, FL, U.S.A.
Divakar SharmaDepartment of Pulmonary and Critical Care, Westchester Medical Center, New York Medical College, Valhalla, NY, U.S.A.
Lawrence DeLorenzoDepartment of Pulmonary and Critical Care, Westchester Medical Center, New York Medical College, Valhalla, NY, U.S.A.
Westchester Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

patientMale, 25 FINAL DIAGNOSIS: Lemierre's disease Symptoms: Back pain • fever • headache • tachycardia • tachypnoe MEDICATION: - Clinical Procedure: - Specialty: Infectious Diseases.

objectiveRare disease.

backgroundLemierre's disease, also known as the forgotten disease, postanginal sepsis, or necrobacillosis, was first reported in 1890 by Courmont and Cade, but it was Dr. Andre Lemierre, a professor of microbiology, who described this disease in 1936. The typical causative agent is Fusobacterium necrophorum, although other organisms may be involved. The pathogenesis of Lemierre's disease is not well understood. It is characterized by a primary oropharyngeal infection associated with septicemia, internal jugular vein thrombosis, and metastatic septic emboli. CASE REPORT: We report a case of Lemierre's disease with bilateral internal jugular vein (IJV) thrombosis and metastatic septic emboli to the lungs and brain, associated with epidural abscess and mycotic aneurysm of the vertebral artery, which is quite rare in Lemierre's disease. This is the first report of a case of Lemierre's disease associated with mycotic aneurysm of the vertebral artery.

conclusionsLemierre's disease is a rare and perplexing medical entity. Clinical suspicion should be high in previously healthy young adults presenting with fever and neck pain following oropharyngeal infection. Dr. Lemierre stated that 'symptoms and signs of Lemierre's disease are so characteristic that it permits diagnosis before bacteriological examination'. The prognosis of patients with Lemierre's disease is generally good, provided prompt recognition and appropriate treatment.

Indexed as

AneurysmInfected – microbiologyLemierre SyndromeThrombosis

Identifiers

PMID24883173
PMCPMC4038640
OpenAlexW2146532806

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.