Evidence map›Paper›PMID 24883075›Full record

ArticleNutrition & metabolism2014

Abdominal obesity is an independent predictor of serum 25-hydroxyvitamin D deficiency in adults with cerebral palsy.

Mark D Peterson, Heidi J Haapala, Ashish Chaddha, Edward A Hurvitz

Open access · goldAbstract read
In one paragraph

Article in Nutrition & metabolism, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mark D PetersonDepartment of Physical Medicine and Rehabilitation, University of Michigan Health Systems, 325 E. Eisenhower Parkway, Suite 300, Ann Arbor, Michigan 48108, USA.
Heidi J HaapalaDepartment of Physical Medicine and Rehabilitation, University of Michigan Health Systems, 325 E. Eisenhower Parkway, Suite 300, Ann Arbor, Michigan 48108, USA.
Ashish ChaddhaDepartment of Physical Medicine and Rehabilitation, University of Michigan Health Systems, 325 E. Eisenhower Parkway, Suite 300, Ann Arbor, Michigan 48108, USA.
Edward A HurvitzDepartment of Physical Medicine and Rehabilitation, University of Michigan Health Systems, 325 E. Eisenhower Parkway, Suite 300, Ann Arbor, Michigan 48108, USA.
Michigan Medicine · US

Funding

Secondary Muscle Pathology & Metabolic Dysregulation in Adult with Cerebral PalsyK01HD074706 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PETERSON, MARK D · 2013 to 2017
$605k
NICHD NIH HHS K01 HD074706
6 · The paper itself

Abstract

backgroundIndividuals with cerebral palsy (CP) are at risk for nutritional insufficiency. The purpose of the study was to examine the vitamin D status of adults with CP, and to evaluate the association between vitamin D and functional level, age, race, and anthropometric indicators of adiposity.

methodsSerum vitamin D levels, BMI, waist circumference (WC), and functional level (measured by Gross Motor Function Classification System (GMFCS)) were examined in 112 adults with CP. Vitamin D status was assessed by serum 25-hydroxyvitamin D level (25(OH)D). The influence of motor impairment and adiposity on 25(OH)D were assessed using general linear modeling and logistic regression, with age, sex, race, and season as covariates.

resultsMean vitamin D was 28.1 ± 16.0 ng/ml. Only 45% of subjects had optimal levels of 25(OH)D, 21% were insufficient and 34% were deficient. Overweight or obesity was prevalent (52%), as was abdominal obesity in men (23.5% at 102 cm cutoff) and women (31.1% at 88 cm cutoff). There was a robust association between the indicator of visceral adiposity (WC) and 25(OH)D level (p <0.001), even after controlling for age, sex, race, season, and GMFCS. According to sex-specific WC cutoffs, the odds of being deficient in vitamin D increase by a factor of 3.5 (95% CI 1.12-11.0) for abdominal obesity. GMFCS was not associated with 25(OH)D.

conclusionsAdults with CP are at risk for low vitamin D levels and overweight/obesity. Waist circumference is a strong independent predictor for low vitamin D levels.

Indexed as

25-hydroxyvitamin DCerebral palsyMotor functionVisceral adiposity

Identifiers

PMID24883075
PMCPMC4039320
OpenAlexW2157056859

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.