ReviewThe Journal of physiology2014
The holist tradition in twentieth century genetics. Wilhelm Johannsen's genotype concept.
Review in The Journal of physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Progress, Challenges, and Surprises in Annotating the Human Genome.Annual review of genomics and human genetics · 2020Review
- How to talk about genome editing.British medical bulletin · 2018Article
- Systems Thinking Versus Population Thinking: Genotype Integration and Chromosomal Organization 1930s-1950s.Journal of the history of biology · 2015Article
- Arsenic, antibiotics and interventions.International journal of epidemiology · 2014Article
- Evolution evolves: physiology returns to centre stage.The Journal of physiology · 2014Article
Corrections and comments
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Authors and funding
1 author.
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Abstract
The terms 'genotype', 'phenotype' and 'gene' originally had a different meaning from that in the Modern Synthesis. These terms were coined in the first decade of the twentieth century by the Danish plant physiologist Wilhelm Johannsen. His bean selection experiment and his theoretical analysis of the difference between genotype and phenotype were important inputs to the formation of genetics as a well-defined special discipline. This paper shows how Johannsen's holistic genotype theory provided a platform for criticism of narrowly genocentric versions of the chromosome theory of heredity that came to dominate genetics in the middle decades of the twentieth century. Johannsen came to recognize the epoch-making importance of the work done by the Drosophila group, but he continued to insist on the incompleteness of the chromosome theory. Genes of the kind that they mapped on the chromosomes could only give a partial explanation of biological heredity and evolution.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.