ReviewThe Journal of physiology2014
From gene action to reactive genomes.
Review in The Journal of physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 145 citations in OpenAlex.
- Toward New Directions in Human Biology: A Roadmap for Anthropological Causal Inference With Observational Data.American journal of human biology : the official journal of the Human Biology Council · 2025Article
- "Snip, snip, cure"? Philosophical, legal and biomedical perspectives on novel somatic genomic therapies.Medicine, health care, and philosophy · 2025Article
- 'Our biology is listening': biomarkers as molecular vestiges of early life and the production of positive childhood experiences in behavioral epigenetics.BioSocieties · 2025Article
- Article
- The Temporal Politics of Placenta Epigenetics: Bodies, Environments and Time.Body & society · 2023Article
- Autopoiesis, Thermodynamics, and the Natural Drift of Living Beings: Another Way to the New Evolutionary Synthesis.Entropy (Basel, Switzerland) · 2022Article
- You Are What Your Mother Endured: Intergenerational Epigenetics, Early Caregiving, and the Temporal Embedding of Adversity.Medical anthropology quarterly · 2021Article
- When is it Safe to Edit the Human Germline?Science and engineering ethics · 2021Article
- Epigenetics and the success of invasive plants.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- Gender Beneath the Skull: Agency, Trauma and Persisting Stereotypes in Neuroepigenetics.Frontiers in human neuroscience · 2021Article
- On the problem of biological form.Theory in biosciences = Theorie in den Biowissenschaften · 2020Article
- Role of Inactivity in Chronic Diseases: Evolutionary Insight and Pathophysiological Mechanisms.Physiological reviews · 2017Review
- Detection of fetal epigenetic biomarkers through genome-wide DNA methylation study for non-invasive prenatal diagnosis.Molecular medicine reports · 2017Article
- The Four Causes of ADHD: Aristotle in the Classroom.Frontiers in psychology · 2017Article
- The Developmental Systems Approach and the Analysis of Behavior.The Behavior analyst · 2016Article
- From boundary-work to boundary object: how biology left and re-entered the social sciences.Sociological review monograph · 2016Article
- The biosocial: sociological themes and issues.Sociological review monograph · 2016Article
- The Significance of an Enhanced Concept of the Organism for Medicine.Evidence-based complementary and alternative medicine : eCAM · 2016Review
- The extended evolutionary synthesis: its structure, assumptions and predictions.Proceedings. Biological sciences · 2015Review
- Evolution evolves: physiology returns to centre stage.The Journal of physiology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Poised at a critical turning point in the history of genetics, recent work (e.g. in genomics, epigenetics, genomic plasticity) obliges us to critically reexamine many of our most basic concepts. For example, I argue that genomic research supports a radical transformation in our understanding of the genome--a shift from an earlier conception of that entity as an effectively static collection of active genes to that of a dynamic and reactive system dedicated to the context specific regulation of protein-coding sequences.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.