ReviewEuropean respiratory review : an official journal of the European Respiratory Society2014
Prone ventilation in acute respiratory distress syndrome.
Review in European respiratory review : an official journal of the European Respiratory Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- EIT-assessed ventilation-perfusion responses to prone positioning and inhaled nitric oxide in mechanically ventilated COVID-19-related ARDS: a prospective sequential study.Journal of intensive care · 2026Article
- Jingfang granules inhibiting LPS-induced acute lung injury via regulating linoleic acid and arachidonic acid metabolism pathway.PloS one · 2026Article
- Translational medicine for acute lung injury.Journal of translational medicine · 2024Review
- Effect of Fu Zheng Jie Du Formula on outcomes in patients with severe pneumonia receiving prone ventilation: a retrospective cohort study.Frontiers in pharmacology · 2024Article
- Volume-controlled ventilation versus pressure-controlled ventilation during spine surgery in the prone position: A meta-analysis.Annals of medicine and surgery (2012) · 2022Review
- Prognostic value of computed tomographic findings in acute respiratory distress syndrome and the response to prone positioning.BMC pulmonary medicine · 2022Article
- Physiological effects and subjective tolerability of prone positioning in COVID-19 and healthy hypoxic challenge.ERJ open research · 2022Article
- Compliance to not only prone but also lateral and supine positioning improves outcome in hospitalised COVID-19 patients.International journal of clinical practice · 2021Article
- Awake Proning for Nonintubated Adult Hypoxic Patients with COVID-19: A Systematic Review of the Published Evidence.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2021Article
- Prone ventilation as treatment of acute respiratory distress syndrome related to COVID-19.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2021Review
- Precision medicine in acute respiratory distress syndrome: workshop report and recommendations for future research.European respiratory review : an official journal of the European Respiratory Society · 2021Review
- Functional pathophysiology of SARS-CoV-2-induced acute lung injury and clinical implications.Journal of applied physiology (Bethesda, Md. : 1985) · 2021Review
- Safe surgical tracheostomy in patients with COVID-19: key clinical considerations.Annals of the Royal College of Surgeons of England · 2021Article
- Intensive Care and Treatment of Severe Guillain-Barré Syndrome.Frontiers in pharmacology · 2021Review
- Reinventing the Wheel in ARDS: Awake Proning in COVID-19.Archivos de bronconeumologia · 2020Article
- A case of improved oxygenation in SARS-CoV-2 positive patient on nasal cannula undergoing prone positioning.Respiratory medicine case reports · 2020Article
- The Fundamentals of Respiratory Physiology to Manage the COVID-19 Pandemic: An Overview.Frontiers in physiology · 2020Review
- ARDS: challenges in patient care and frontiers in research.European respiratory review : an official journal of the European Respiratory Society · 2018Review
- Treatment of ARDS With Prone Positioning.Chest · 2017Review
- The Emulsified PFC OxycyteLung · 2016Article
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Prone positioning has been used for many years in patients with acute lung injury (ALI)/acute respiratory distress syndrome (ARDS), with no clear benefit for patient outcome. Meta-analyses have suggested better survival in patients with an arterial oxygen tension (PaO2 )/inspiratory oxygen fraction (FIO2 ) ratio <100 mmHg. A recent randomised controlled trial was performed in ARDS patients after a 12-24 h stabilisation period and severity criteria (PaO2 /FIO2 <150 mmHg at a positive end-expiratory pressure ≥5 cmH2O). This trial has demonstrated a significant reduction in mortality from 32.8% in the supine group to 16% in the prone group (p<0.001). The reasons for this dramatic effect are not clear but probably involves a reduction in ventilator-induced lung injury due to prone positioning, for which there is ample evidence in experimental and clinical studies. The aims of this article are to discuss: the rationale of prone positioning in patients with ALI/ARDS; the evidence of its use based on trial analysis; and the limitations of its use as well as the current place of prone positioning in the management of patients with ALI/ARDS. From the currently available data, prone positioning should be used as a first-line therapy in patients with severe ALI/ARDS.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.