ArticleJournal of behavioral medicine2015
Disentangling Multiple Sclerosis and depression: an adjusted depression screening score for patient-centered care.
Article in Journal of behavioral medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Psychometric properties of the PHQ-9 depression scale in people with multiple sclerosis: A systematic review.PloS one · 2019Pooled it
- Optimizing Identification and Management of Depression in Neurological Diseases: A Narrative Review and Expert Perspective.Neuropsychiatric disease and treatment · 2026Article
- Using latent variables to improve the management of depression among hemodialysis patients.Renal failure · 2024Article
- Study protocol: exercise training for treating major depressive disorder in multiple sclerosis.BMC neurology · 2024Article
- A Comparison of Depressive Symptom Presentation in Adolescent Type 1 Diabetes and Pediatric Primary Care Samples.Pediatric diabetes · 2023Article
- Patient-Centered Care for Patients with Depression or Anxiety Disorder: An Integrative Review.Journal of personalized medicine · 2021Review
- The Effect of Depression on Health-Related Quality of Life Is Mediated by Fatigue in Persons with Multiple Sclerosis.Brain sciences · 2021Article
- Article
- Identify depressive phenotypes by applying RDOC domains to the PHQ-9.Psychiatry research · 2020Article
- Smokers with MS have greater decrements in quality of life and disability than non-smokers.Multiple sclerosis (Houndmills, Basingstoke, England) · 2017Article
- Mental Health Comorbidity in MS: Depression, Anxiety, and Bipolar Disorder.Current neurology and neuroscience reports · 2016Review
- Heterogeneous depression trajectories in multiple sclerosis patients.Multiple sclerosis and related disorders · 2016Article
- A tutorial on structural equation modeling for analysis of overlapping symptoms in co-occurring conditions using MPlus.Statistics in medicine · 2015Article
- Magnitude and concurrence of anxiety and depression among attendees with multiple sclerosis at a tertiary care Hospital in Oman.BMC neurology · 2015Article
- Training a Nonclinician to Become a Leader in Transdisciplinary Clinical Research: Clinical Observerships.International journal of clinical biostatistics and biometrics · 2015Article
- Effect of Multiple Sclerosis on Daily Activities, Emotional Well-being, and Relationships: The Global vsMS Survey.International journal of MS careArticle
- Fatigue and Comorbidities in Multiple Sclerosis.International journal of MS careArticle
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
Abstract
Screening for depression can be challenging in Multiple Sclerosis (MS) patients due to the overlap of depressive symptoms with other symptoms, such as fatigue, cognitive impairment and functional impairment, for MS patients. The aim of this study was to understand these overlapping symptoms and subsequently develop an adjusted depression screening tool for better clinical assessment of depressive symptoms in MS patients. We evaluated 3,507 MS patients with a self-reported depression screening (PHQ-9) score using a multiple indicator multiple cause modeling approach. Our models showed significant differential item functioning effects denoting significant overlap of depressive symptoms with all MS symptoms under study and good model fit. The magnitude of the overlap was especially large for fatigue. Adjusted depression screening scales were formed based on factor scores and loadings that will allow clinicians to understand the depressive symptoms separate from other symptoms for MS patients for improved patient care.
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Registered trials
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