Evidence map›Paper›PMID 24879998›Full record

ArticleJournal of pain and symptom management2014

Ethical conduct of palliative care research: enhancing communication between investigators and institutional review boards.

Amy P Abernethy, Warren H Capell, Noreen M Aziz, Christine Ritchie, Maryjo Prince-Paul, Rachael E Bennett, Jean S Kutner

Abstract read
In one paragraph

Article in Journal of pain and symptom management, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Intersectionality-Informed HIV Cure-Related Research at the End of Life: A Call to Action.International journal of environmental research and public health · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Observational
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amy P AbernethyDuke Clinical Research Institute, Durham, North Carolina, USA; Duke Cancer Institute, Duke University School of Medicine, Durham, North Carolina, USA.
Warren H CapellUniversity of Colorado School of Medicine, Aurora, Colorado, USA.
Noreen M AzizDivision of Extramural Activities, National Institute of Nursing Research, National Institutes of Health, Bethesda, Maryland, USA.
Christine RitchieUniversity of California at San Francisco, San Francisco, California, USA.
Maryjo Prince-PaulFrances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, Ohio, USA.
Rachael E BennettUniversity of Colorado School of Medicine, Aurora, Colorado, USA.
Jean S KutnerUniversity of Colorado School of Medicine, Aurora, Colorado, USA. Electronic address: Jean.Kutner@ucdenver.edu.

Funding

Refinement and Expansion of the Palliative Care Research Cooperative Group (PCRC)U24NR014637 · NINR · DUKE UNIVERSITY · PI KUTNER, JEAN S, POLLAK, KATHRYN I · 2013 to 2017
$9.6M
Palliative Care Research Cooperative Group (PCRC): Refinement and ExpansionU2CNR014637 · NINR · UNIVERSITY OF COLORADO DENVER · PI COLBORN, KATHRYN LOUISE · 2018 to 2022
$8.6M
Creation and demonstration of a palliative care research cooperative groupUC4NR012584 · NINR · DUKE UNIVERSITY · PI ABERNETHY, AMY P., KUTNER, JEAN S · 2010 to 2010
$7.2M
NINR NIH HHS 1UC4NR012584-01NINR NIH HHS U24 NR014637NINR NIH HHS U2C NR014637NINR NIH HHS UC4 NR012584
6 · The paper itself

Abstract

Palliative care has faced moral and ethical challenges when conducting research involving human subjects. There are currently no resources to guide institutional review boards (IRBs) in applying standard ethical principles and terms-in a specific way-to palliative care research. Using as a case study a recently completed multisite palliative care clinical trial, this article provides guidance and recommendations for both IRBs and palliative care investigators to facilitate communication and attain the goal of conducting ethical palliative care research and protecting study participants while advancing the science. Beyond identifying current challenges faced by palliative care researchers and IRBs reviewing palliative care research, this article suggests steps that the palliative care research community can take to establish a scientifically sound, stable, productive, and well-functioning relationship between palliative care investigators and the ethical bodies that oversee their work.

Indexed as

Ethics, ResearchClinical Trials as TopicCommunicationEthics Committees, ResearchHumansMulticenter Studies as TopicPalliative CareResearch Personnelhuman subjects protectioninstitutional review boardsPalliative careresearch ethics

Identifiers

PMID24879998
PMCPMC4247357

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.