ReviewThe Journal of physiology2014
Nociceptive primary afferents: they have a mind of their own.
Review in The Journal of physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed.
- Lateral lamina V projection neuron axon collaterals connect sensory processing across the dorsal horn of the mouse spinal cord.Scientific reports · 2024Article
- Toward a brighter constellation: multiorgan neuroimaging of neural and vascular dynamics in the spinal cord and brain.Neurophotonics · 2024Article
- Intraspinal microstimulation of the ventral horn has therapeutically relevant cross-modal effects on nociception.Brain communications · 2024Article
- Towards a Brighter Constellation: Multi-Organ Neuroimaging of Neural and Vascular Dynamics in the Spinal Cord and Brain.bioRxiv : the preprint server for biology · 2023Article
- Review
- Age-related changes in peripheral nociceptor function.Neuropharmacology · 2022Article
- Neuronal-Immune Cell Units in Allergic Inflammation in the Nose.International journal of molecular sciences · 2022Review
- Advancing the Understanding of Acupoint Sensitization and Plasticity Through Cutaneous C-Nociceptors.Frontiers in neuroscience · 2022Review
- Renal Nerve Ablation in Nephritis and Beyond.Journal of the American Society of Nephrology : JASN · 2021Article
- Renal Denervation Exacerbates LPS- and Antibody-induced Acute Kidney Injury, but Protects from Pyelonephritis in Mice.Journal of the American Society of Nephrology : JASN · 2021Article
- Neurogenic substance P-influences on action potential production in afferent neurons of the kidney?Pflugers Archiv : European journal of physiology · 2021Article
- Neurogenic tachykinin mechanisms in experimental nephritis of rats.Pflugers Archiv : European journal of physiology · 2020Article
- Central processing of afferent renal pathways-significance and implications.Pflugers Archiv : European journal of physiology · 2020Article
- Expression and effect of sodium-potassium-chloride cotransporter on dorsal root ganglion neurons in a rat model of chronic constriction injury.Neural regeneration research · 2020Article
- Pituitary Adenylate Cyclase-Activating Polypeptide: 30 Years in Research Spotlight and 600 Million Years in Service.Journal of clinical medicine · 2019Review
- Plasma Protein Pattern Correlates With Pain Intensity and Psychological Distress in Women With Chronic Widespread Pain.Frontiers in psychology · 2018Article
- Morphological and functional diversity of first-order somatosensory neurons.Biophysical reviews · 2017Review
- Neuro-immune interactions in allergic diseases: novel targets for therapeutics.International immunology · 2017Article
- Exploring the Mechanisms of Exercise-Induced Hypoalgesia Using Somatosensory and Laser Evoked Potentials.Frontiers in physiology · 2016Article
- Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
Nociceptive primary afferents have three surprising properties: they are highly complex in their expression of neurotransmitters and receptors and most probably participate in autocrine and paracrine interactions; they are capable of exerting tonic and activity-dependent inhibitory control over incoming nociceptive input; they can generate signals in the form of dorsal root reflexes that are transmitted antidromically out to the periphery and these signals can result in neurogenic inflammation in the innervated tissue. Thus, nociceptive primary afferents are highly complicated structures, capable of modifying input before it is ever transmitted to the central nervous system and capable of altering the tissue they innervate.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.