ArticleVascular medicine (London, England)2014
The impact of change in physical activity on change in arterial stiffness in overweight or obese sedentary young adults.
Article in Vascular medicine (London, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00366990 (Clinical Trial to Reverse Early Arterial Stiffening), which is not on this map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical Trial to Reverse Early Arterial Stiffening
Who cites it
12 citing papers in PubMed, 29 citations in OpenAlex.
- Physical activity and arterial stiffness: is body fat a mediator?European journal of applied physiology · 2024Article
- Relationship between objectively measured physical activity and subclinical cardiovascular disease: a systematic review.BMJ open sport & exercise medicine · 2024Article
- Vascular hemodynamics and blood pressure differences between young and older women.Clinical hypertension · 2021Article
- Predictors of Arterial Stiffness in Law Enforcement Officers.International journal of environmental research and public health · 2021Article
- Higher Total Physical Activity is Associated with Lower Arterial Stiffness in Swedish, Young Adults: The Cross-Sectional Lifestyle, Biomarkers, and Atherosclerosis Study.Vascular health and risk management · 2021Article
- Interindividual Variability in Fat Mass Response to a 1-Year Randomized Controlled Trial With Different Exercise Intensities in Type 2 Diabetes: Implications on Glycemic Control and Vascular Function.Frontiers in physiology · 2021Article
- Optical measures of cerebral arterial stiffness are associated with white matter signal abnormalities and cognitive performance in normal aging.Neurobiology of aging · 2019Article
- Physical activity trajectories and mortality: population based cohort study.BMJ (Clinical research ed.) · 2019Article
- Arterial stiffness and hypertension.Clinical hypertension · 2018Review
- Association of Central Arterial Stiffness and Pressure Pulsatility with Mild Cognitive Impairment and Dementia: The Atherosclerosis Risk in Communities Study-Neurocognitive Study (ARIC-NCS).Journal of Alzheimer's disease : JAD · 2017Article
- Mapping cerebral pulse pressure and arterial compliance over the adult lifespan with optical imaging.PloS one · 2017Article
- Physical activity is associated with lower arterial stiffness in older adults: results of the SAPALDIA 3 Cohort Study.European journal of epidemiology · 2016Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
Arterial stiffness is associated with cardiovascular events and mortality. Lifestyle factors such as physical activity (PA) may reduce arterial stiffness. The purpose of this study is to determine the impact of change in PA on 1-year change in arterial stiffness in 274 overweight/obese sedentary young adults. The Slow Adverse Vascular Effects of excess weight (SAVE) trial was a study evaluating the relationships between weight loss, dietary sodium, and vascular health. PA was measured with the ActiGraph AM7164 accelerometer. Intensity of activity was determined using established cut-points. Arterial stiffness was assessed by brachial-ankle pulse wave velocity (baPWV) using an automated device. Analysis of covariance compared changes in total accelerometer counts, minutes/day in light-intensity PA (LPA), moderate-to-vigorous PA (MVPA), and sedentary time, by categories of change in baPWV. Models were adjusted for time since baseline visit, age, sex, race, homeostatis model of assessment of insulin resistance, mean arterial pressure, heart rate, and weight change. Total accelerometer counts and time spent in MVPA increased from baseline to 12 months while time spent in LPA significantly decreased. Mean baPWV was similar at each time point. Those who showed decreased baPWV also showed an increase in total accelerometer counts per day and time spent in MVPA in the fully adjusted models (p<0.001). Changes in sedentary time and time spent in LPA were not associated with changes in baPWV. These results indicate that even modest increases in MVPA can reduce arterial stiffness, a risk factor for future cardiovascular events.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.