ReviewCurrent rheumatology reports2014
New insights into the benefits of exercise for muscle health in patients with idiopathic inflammatory myositis.
Review in Current rheumatology reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Physical exercise for dermatomyositis and polymyositis: a systematic review and meta-analysis.Clinical rheumatology · 2022Pooled it
- Physical therapy in adult inflammatory myopathy patients: a systematic review.Clinical rheumatology · 2019Pooled it
- The Role of Exercise to Improve Physiological, Physical and Psychological Health Outcome in Idiopathic Inflammatory Myopathies (IIM).Journal of inflammation research · 2024Review
- Effects of Exercise on Body Composition and Physical Function in Rheumatoid Arthritis Patients: Scoping Review.Open access rheumatology : research and reviews · 2023Article
- Harnessing the benefits of yoga for myositis, muscle dystrophies, and other musculoskeletal disorders.Clinical rheumatology · 2022Review
- Celecoxib impairs primary human myoblast proliferation and differentiation independent of cyclooxygenase 2 inhibition.Physiological reports · 2022Article
- Improved skeletal muscle fatigue resistance in experimental autoimmune myositis mice following high-intensity interval training.Arthritis research & therapy · 2022Article
- Physical activity in idiopathic inflammatory myopathies: two intervention proposals based on literature review.Clinical rheumatology · 2022Review
- Exercise as a multi-modal disease-modifying medicine in systemic sclerosis: An introduction by The Global Fellowship on Rehabilitation and Exercise in Systemic Sclerosis (G-FoRSS).Best practice & research. Clinical rheumatology · 2021Review
- Immune-mediated necrotizing myopathy: clinical features and pathogenesis.Nature reviews. Rheumatology · 2020Review
- Idiopathic inflammatory myopathy human derived cells retain their ability to increase mitochondrial function.PloS one · 2020Article
- Exercise in Myositis.Current treatment options in rheumatology · 2018Review
- Mortality and Causes of Death in Patients with Sporadic Inclusion Body Myositis: Survey Study Based on the Clinical Experience of Specialists in Australia, Europe and the USA.Journal of neuromuscular diseases · 2016Article
- Proposal for a Candidate Core Set of Fitness and Strength Tests for Patients with Childhood or Adult Idiopathic Inflammatory Myopathies.The Journal of rheumatology · 2016Review
- Physical impairment in patients with idiopathic inflammatory myopathies is associated with the American College of Rheumatology functional status measure.Clinical rheumatology · 2015Article
- Demographic and clinical features of inclusion body myositis in North America.Muscle & nerve · 2015Article
- Idiopathic inflammatory myopathies-a review.Clinical rheumatology · 2015Review
- Ongoing developments in sporadic inclusion body myositis.Current rheumatology reports · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
With recommended treatment, a majority with idiopathic inflammatory myopathy (IIM) develop muscle impairment and poor health. Beneficial effects of exercise have been reported on muscle performance, aerobic capacity and health in chronic polymyositis and dermatomyositis and to some extent in active disease and inclusion body myositis (IBM). Importantly, randomized controlled trials (RCTs) indicate that improved health and decreased clinical disease activity could be mediated through increased aerobic capacity. Recently, reports seeking mechanisms underlying effects of exercise in skeletal muscle indicate increased aerobic capacity (i.e. increased mitochondrial capacity and capillary density, reduced lactate levels), activation of genes in aerobic phenotype and muscle growth programs, and down regulation in genes related to inflammation. Altogether, exercise contributes to both systemic and within-muscle adaptations demonstrating that exercise is fundamental to improve muscle performance and health in IIM. There is a need for RCTs to study effects of exercise in active disease and IBM.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.