Evidence map›Paper›PMID 24879519›Full record

ArticleJournal of assisted reproduction and genetics2014

Chromosome distribution of early miscarriages with present or absent embryos: female predominance.

Hsin-Hsin Cheng, Chia-Yu Ou, Ching-Chang Tsai, Shuenn-Dyh Chang, Pi-Yu Hsiao, Kuo-Chung Lan, Te-Yao Hsu

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Journal of assisted reproduction and genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Ultrasound features in early pregnancy for predicting abnormal karyotype in first-trimester miscarriage.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2026
    Observational
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  13. [Blighted ovum in subfertile patients undergoing assisted reproductive technology].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2017
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Hsin-Hsin ChengDepartment of Obstetrics and Gynecology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, 123, Ta-Pei Road, Niao-Sung Dist., Kaohsiung, 833, Taiwan, chokovarous@hotmail.com.
Chia-Yu Ou
Ching-Chang Tsai
Shuenn-Dyh Chang
Pi-Yu Hsiao
Kuo-Chung Lan
Te-Yao Hsu
Chang Gung University · TWKaohsiung Chang Gung Memorial Hospital · TWChang Gung Memorial Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe objective of this study is to compare the chromosomal distribution of early miscarriages with or without embryonic poles. MATERIALS AND

methodsIt was a retrospective study of 223 women who underwent dilation and curettage (D&C) between 1995 and 2013 for early miscarriages. The presence or absence of a fetal pole was evaluated by abdominal or transvaginal ultrasound. Cytogenetic tests of products of conception following culture were determined in both groups.

resultsOf the 223 early miscarriages, 143 had embryos and 80 did not. The abnormality rate differed significantly (61.5 % vs. 46.3 %, p < 0.05), with trisomy 18, 21 and 45X found only in miscarriages with embryos. There were no significant differences between groups in rates of triploidy, tetraploidy, mosaicism, structure and double abnormality. The female abortus rate was higher in miscarriages with or without embryonic poles, as well as in groups with normal and abnormal karyotypes.

conclusionsChromosome distribution differs in miscarriages with or without embryonic poles. The ultrasound findings might offer different direction to determine the causes of early miscarriages. The higher female abortus rate may be associated with early selection.

Indexed as

Chromosome AberrationsAbortion, SpontaneousAdultCurettageEmbryo LossEmbryo, MammalianFemaleHumansKaryotypePregnancyPregnancy ComplicationsRetrospective Studies

Identifiers

PMID24879519
PMCPMC4130929
OpenAlexW2005727299

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.