ReviewCurrent opinion in microbiology2014
Fungal pathogens are platforms for discovering novel and conserved septin properties.
Review in Current opinion in microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 27 citations in OpenAlex.
- CWI-MAPKs Regulate the Formation of Hyphopodia Required for Virulence in Ceratocystis fimbriata.Molecular plant pathology · 2025Article
- Article
- Insights of roles played by septins in pathogenic fungi.Virulence · 2021Review
- Discovery of broad-spectrum fungicides that block septin-dependent infection processes of pathogenic fungi.Nature microbiology · 2020Article
- The LKB1-like Kinase Elm1 Controls Septin Hourglass Assembly and Stability by Regulating Filament Pairing.Current biology : CB · 2020Article
- MCC/Eisosomes Regulate Cell Wall Synthesis and Stress Responses in Fungi.Journal of fungi (Basel, Switzerland) · 2017Review
- Mechanics and regulation of cytokinesis in budding yeast.Seminars in cell & developmental biology · 2017Review
- Mechanisms of Cytokinesis in Basidiomycetous Yeasts.Fungal biology reviews · 2017Article
- Septins Focus Cellular Growth for Host Infection by Pathogenic Fungi.Frontiers in cell and developmental biology · 2017Review
- The Nim1 kinase Gin4 has distinct domains crucial for septin assembly, phospholipid binding and mitotic exit.Journal of cell science · 2016Article
- Septin 9 induces lipid droplets growth by a phosphatidylinositol-5-phosphate and microtubule-dependent mechanism hijacked by HCV.Nature communications · 2016Article
- The DenA/DEN1 Interacting Phosphatase DipA Controls Septa Positioning and Phosphorylation-Dependent Stability of Cytoplasmatic DenA/DEN1 during Fungal Development.PLoS genetics · 2016Article
- Visualization of in vivo septin ultrastructures by platinum replica electron microscopy.Methods in cell biology · 2016Article
- Septin Form and Function at the Cell Cortex.The Journal of biological chemistry · 2015Review
- Expression of Septin4 in Schistosoma japonicum-infected mouse livers after praziquantel treatment.Parasites & vectors · 2015Article
- Article
- Septins and Generation of Asymmetries in Fungal Cells.Annual review of microbiology · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Septins are filament-forming GTP-binding proteins that act as scaffolds in diverse cell functions including division, polarity and membrane remodeling. In a variety of fungal pathogens, it has been observed that septins are required for virulence because cells are unable to survive or are misshapen when septins are mutated. Cell morphology is interconnected with pathogenesis and thus septin mutants displaying aberrant cell morphologies are commonly deficient in host tissue invasion. The degree to which septins orchestrate versus maintain changes in fungal cell morphology during pathogenesis remains to be determined. Aside from the importance of septins in the process of pathogenesis, animal and plant fungal pathogens display complexity in septin form, dynamics, and function not seen in Saccharomyces cerevisiae making these organisms important models for uncovering diversity in septin behavior. Additionally, host septins have recently been implicated in the process of Candida albicans invasion, motivating the need to examine host septins in fungal pathogenesis. Understanding the role of septins in the host-pathogen interaction not only illuminates pathogenesis mechanisms but importantly also expands our understanding of septin biology in general.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.