Evidence map›Paper›PMID 24879423›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2014

Defining the radiobiology of prostate cancer progression: An important question in translational prostate cancer research.

Srinivas Vourganti, Jeffrey Donaldson, Linda Johnson, Baris Turkbey, Gennady Bratslavsky, Leszek Kotula

Abstract read
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Srinivas VourgantiDepartment of Urology, SUNY Upstate Medical University, Syracuse, NY 13210, USA vourgans@upstate.edu kotulal@upstate.edu.
Jeffrey DonaldsonDepartment of Urology, SUNY Upstate Medical University, Syracuse, NY 13210, USA.
Linda JohnsonMolecular Imaging Program, Urologic Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Baris TurkbeyMolecular Imaging Program, Urologic Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Gennady BratslavskyDepartment of Urology, SUNY Upstate Medical University, Syracuse, NY 13210, USA.
Leszek KotulaDepartment of Urology, SUNY Upstate Medical University, Syracuse, NY 13210, USA Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, Syracuse, NY 13210, USA.

Funding

Mechanism of PIN development in Abi1/Hssh3bp1 KO mouseR01CA161018 · NCI · UPSTATE MEDICAL UNIVERSITY · PI KOTULA, LESZEK · 2013 to 2017
$1.7M
NCI NIH HHS R01 CA161018
6 · The paper itself

Abstract

Prostate cancer is one of the most common malignancies affecting men worldwide. High mortality rates from advanced and metastatic prostate cancer in the United States are contrasted by a relatively indolent course in the majority of cases. This gives hope for finding methods that could direct personalized diagnostic, preventative, and treatment approaches to patients with prostate cancer. Recent advances in multiparametric magnetic resonance imaging (MP-MRI) offer a noninvasive diagnostic intervention which allows correlation of prostate tumor image characteristics with underlying biologic evidence of tumor progression. The power of MP-MRI includes examination of both local invasion and nodal disease and might overcome the challenges of analyzing the multifocal nature of prostate cancer. Future directions include a careful analysis of the genomic signature of individual prostatic lesions utilizing image-guided biopsies. This review examines the diagnostic potential of MRI in prostate cancer.

Indexed as

image-guided biopsylymph node imagingmagnetic resonance imagingProstate cancerradiobiology

Identifiers

PMID24879423
PMCPMC4478242

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.