ArticleSurgical endoscopy2014
NOTES total mesorectal excision (TME) for patients with rectal neoplasia: a preliminary experience.
Article in Surgical endoscopy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 3 syntheses or guidelines pooled it, 79 citations in OpenAlex.
- Clinical outcomes and case volume effect of transanal total mesorectal excision for rectal cancer: a systematic review.Techniques in coloproctology · 2016Pooled it
- Transanal total mesorectal excision for rectal cancer: a single center experience and systematic review of the literature.Langenbeck's archives of surgery · 2015Pooled it
- Transanal total mesorectal excision: a systematic review of the experimental and clinical evidence.Techniques in coloproctology · 2015Pooled it
- Robotic Transanal Surgery for Rectal Cancer.Clinics in colon and rectal surgery · 2021Review
- Robotic-assisted transanal total mesorectal excision for rectal cancer: technique and results from a single institution.Techniques in coloproctology · 2021Article
- SP rTaTME: initial clinical experience with single-port robotic transanal total mesorectal excision (SP rTaTME).Techniques in coloproctology · 2021Article
- Transanal Surgery: A History of taTME Ancestry.Clinics in colon and rectal surgery · 2020Review
- Trans-stomal single-port laparoscopic Hartmann's reversal is an efficacious and efficient procedure: a case-controlled study.Techniques in coloproctology · 2020Article
- Robotic surgery for colorectal disease: review of current port placement and future perspectives.Annals of surgical treatment and research · 2020Article
- Novel box trainer for taTME - prospective evaluation among medical students.Innovative surgical sciences · 2019Article
- Direct target NOTES: prospective applications for next generation robotic platforms.Techniques in coloproctology · 2018Article
- Evolution of transanal total mesorectal excision for rectal cancer: From top to bottom.World journal of gastrointestinal surgery · 2018Review
- Lower Gastrointestinal Surgery: Robotic Surgery versus Laparoscopic Procedures.Visceral medicine · 2018Review
- Transanal Total Mesorectal Excision: A Novel Approach to Rectal Surgery.Clinics in colon and rectal surgery · 2017Review
- Combined robotic transanal total mesorectal excision (R-taTME) and single-site plus one-port (R-SSPO) technique for ultra-low rectal surgery-initial experience with a new operation approach.International journal of colorectal disease · 2017Article
- Article
- Re-appraisal and consideration of minimally invasive surgery in colorectal cancer.Gastroenterology report · 2017Review
- True NOTES TME resection with splenic flexure release, high ligation of IMA, and side-to-end hand-sewn coloanal anastomosis.Surgical endoscopy · 2016Article
- Transanal NOTES total mesorectal excision (TME) in patients with rectal cancer: Is anatomy better preserved?Techniques in coloproctology · 2016Article
- Endolumenal colon occlusion reduces peritoneal contamination during a transrectal NOTES procedure: a controlled porcine survival study.Surgical endoscopy · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNatural orifice transluminal endoscopic surgery (NOTES) and single-incision laparoscopy are emerging, minimally invasive techniques. Total mesorectal excision (TME), the gold standard treatment for patients with resectable distal rectal tumors, is usually performed in an "up-to-down" approach, either laparoscopically or via open techniques. A transanal, "down-to-up" TME has already been reported. Our NOTES variant of TME (NOTESTME) is based on a transperineal approach without any form of abdominal assistance. The aim was to reduce further the invasiveness of the procedure while optimizing the anatomical definition of the distal mesorectum. This approach may lead to reduced postoperative pain, decreased hernia formation and improved cosmesis when compared to standard laparoscopy.
methodsNOTESTME was attempted in 16 patients with distal rectal neoplasia (i.e., distal edge of the tumor lower than the pouch of Douglas, between 0 and 12 cm from the dentate line). Additional inclusion criteria consisted of an ASA status ≤III and the absence of previous abdominal surgery.
resultsNOTESTME was completed in all patients. Additional abdominal, single-incision laparoscopic assistance was required in 6 (38 %) patients. Mean operative time was 265 min (range 155-440 min). The morbidity rate was 18.8 % (two small bowel obstructions and one pelvic abscess), requiring re-operation in each case. No leaks occurred, and the mortality rate at 30 and 90 days was 0 %. Resection margins were negative in all patients. A median of 17 nodes (range 12-81) was retrieved per specimen. Mean length of hospital stay was 10 days (range 4-29 days). Patients were followed for an average of 7 months (range 3-23 months).
conclusionNOTESTME was feasible and safe in this series of patients with mid- or low rectal tumors. The short-term mortality and morbidity rates are acceptable, with no apparent compromise in the oncological quality of the resection. Larger, randomized controlled trials with long-term follow-up are warranted.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.