Evidence map›Paper›PMID 24878996›Full record

ArticleRevista do Instituto de Medicina Tropical de Sao Paulo

Resistance to amoxicillin, clarithromycin and ciprofloxacin of Helicobacter pylori isolated from Southern Brazil patients.

Simone Ulrich Picoli, Luiz Edmundo Mazzoleni, Heriberto Fernández, Laura Renata De Bona, Erli Neuhauss, Larisse Longo, João Carlos Prolla

Open access · diamondAbstract read
In one paragraph

Article in Revista do Instituto de Medicina Tropical de Sao Paulo. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Helicobacter pylori eradication: influence of interleukin-1beta -31 C/T polymorphism.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Trial
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  9. Prevalence of Infection and Antibiotic Susceptibility ofPathogens (Basel, Switzerland) · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Simone Ulrich PicoliInstitute of Health Sciences, Universidade Feevale, Novo Hamburgo, RS, Brazil.
Luiz Edmundo MazzoleniSchool of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Heriberto FernándezInstitute of Clinical Microbiology, School of Medicine, Universidad Austral de Chile, Valdivia, Chile.
Laura Renata De BonaHospital de Clínicas de Porto Alegre, Service of Gastroenterology, Porto Alegre, RS, Brazil.
Erli NeuhaussCentro Universitário Metodista, Porto Alegre, RS, Brazil.
Larisse LongoHospital de Clínicas de Porto Alegre, Service of Gastroenterology, Porto Alegre, RS, Brazil.
João Carlos ProllaPrograma de Pós-Graduação em Gastroenterologia e Hepatologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Universidade Federal do Rio Grande do Sul · BRAustral University of Chile · CLCentro Universitário Metodista IPA · BRUniversidade Feevale · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHelicobacter pylori is a bacteria which infects half the world population and is an important cause of gastric cancer. The eradication therapy is not always effective because resistance to antimicrobials may occur. The aim of this study was to determine the susceptibility profile of H. pylori to amoxicillin, clarithromycin and ciprofloxacin in the population of Southern Brazil. MATERIAL AND

methodsFifty four samples of H. pylori were evaluated. The antibiotics susceptibility was determined according to the guidelines of the British Society for Antimicrobial Chemotherapy and the Comité de l'Antibiogramme de la Société Française de Microbiologie.

resultsSix (11.1%) H. pylori isolates were resistant to clarithromycin, one (1.9%) to amoxicillin and three (5.5%) to ciprofloxacin. These indices of resistance are considered satisfactory and show that all of these antibiotics can be used in the empirical therapy.

conclusionThe antibiotics amoxicillin and clarithromycin are still a good option for first line anti-H. pylori treatment in the population of Southern Brazil.

Indexed as

Drug Resistance, BacterialAdultAgedAged, 80 and overAmoxicillinAnti-Bacterial AgentsCiprofloxacinClarithromycinHelicobacter InfectionsHelicobacter pyloriHumansMicrobial Sensitivity TestsMiddle AgedYoung AdultAmoxicillinAnti-Bacterial AgentsCiprofloxacinClarithromycin

Identifiers

PMID24878996
PMCPMC4085860
OpenAlexW2041275896

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.