Trial reportJournal of medical Internet research2014
Effectiveness of a Web-based tailored intervention (E-health4Uth) and consultation to promote adolescents' health: randomized controlled trial.
Trial report in Journal of medical Internet research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 15 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 15 syntheses or guidelines pooled it, 88 citations in OpenAlex.
- Effects of Digital Health Interventions to Promote Safer Sex Behaviors Among Youth: Systematic Review and Bayesian Network Meta-Analysis.Journal of medical Internet research · 2026Pooled it
- What's the 'Secret Sauce'?: A Systematic Review of the Characteristics of Effective Digital Health Behaviour Change Interventions for Children and Adolescents.Health promotion journal of Australia : official journal of Australian Association of Health Promotion Professionals · 2025Pooled it
- Mobile phone-based interventions for improving contraception use.The Cochrane database of systematic reviews · 2023Pooled it
- mHealth Interventions to Reduce Alcohol Use in Young People: A Systematic Review of the Literature.Comprehensive child and adolescent nursing · 2020Pooled it
- Pooled it
- Developing young men's wellbeing through community and school-based programs: A systematic review.PloS one · 2019Pooled it
- Individual-, family-, and school-level interventions targeting multiple risk behaviours in young people.The Cochrane database of systematic reviews · 2018Pooled it
- Technology-Based Interventions to Reduce Sexually Transmitted Infections and Unintended Pregnancy Among Youth.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2018Pooled it
- Tobacco cessation interventions for young people.The Cochrane database of systematic reviews · 2017Pooled it
- Internet-based interventions for smoking cessation.The Cochrane database of systematic reviews · 2017Pooled it
- The quality and effectiveness of interventions that target multiple risk factors among young people: a systematic review.Australian and New Zealand journal of public health · 2017Pooled it
- Cognitive behavioural therapy (CBT), third-wave CBT and interpersonal therapy (IPT) based interventions for preventing depression in children and adolescents.The Cochrane database of systematic reviews · 2016Pooled it
- School-based interventions for improving contraceptive use in adolescents.The Cochrane database of systematic reviews · 2016Pooled it
- Socioeconomic gradients in the effects of universal school-based health behaviour interventions: a systematic review of intervention studies.BMC public health · 2015Pooled it
- Mobile phone-based interventions for improving contraception use.The Cochrane database of systematic reviews · 2015Pooled it
- Effectiveness of tailored multichannel interventions on weight loss among adolescents: a randomized controlled trial.Frontiers in public health · 2026Trial
- The MOSEXY trial: mobile phone intervention for sexual health in youth-a pragmatic randomised controlled trial to evaluate the effect of a smartphone application on sexual health in youth in Stockholm, Sweden.Sexually transmitted infections · 2021Trial
- A Web-Based, Computer-Tailored Intervention to Reduce Alcohol Consumption and Binge Drinking Among Spanish Adolescents: Cluster Randomized Controlled Trial.Journal of medical Internet research · 2020Trial
- Design, implementation and evaluation of a web-based computer-tailored intervention to prevent binge drinking in adolescents: study protocol.BMC public health · 2018Trial
- Personalized Web-Based Advice in Combination With Well-Child Visits to Prevent Overweight in Young Children: Cluster Randomized Controlled Trial.Journal of medical Internet research · 2017Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo promote well-being and health behaviors among adolescents, 2 interventions were implemented at 12 secondary schools. Adolescents in the E-health4Uth group received Web-based tailored messages focused on their health behaviors and well-being. Adolescents in the E-health4Uth and consultation group received the same tailored messages, but were subsequently referred to a school nurse for a consultation if they were at risk of mental health problems.
objectiveThis study evaluated the effect of E-health4Uth and E-health4Uth and consultation on well-being (ie, mental health status and health-related quality of life) and health behaviors (ie, alcohol and drug use, smoking, safe sex).
methodsA cluster randomized controlled trial was conducted among third- and fourth-year secondary school students (mean age 15.9, SD 0.69). School classes (clusters) were randomly assigned to (1) E-health4Uth group, (2) E-health4Uth and consultation group, or (3) control group (ie, care as usual). Adolescents completed a questionnaire at baseline and at 4-month follow-up assessing alcohol consumption, smoking, drug use, condom use, mental health via the Strengths and Difficulties Questionnaire (SDQ) and the Youth Self Report (YSR; only measured at follow-up), and health-related quality of life. Multilevel logistic, ordinal, and linear regression analyses were used to reveal differences in health behavior and well-being between the intervention groups and the control group at follow-up. Subsequently, it was explored whether demographics moderated the effects.
resultsData from 1256 adolescents were analyzed. Compared to the control intervention, the E-health4Uth intervention, as a standalone intervention, showed minor positive results in health-related quality of life (B=2.79, 95% CI 0.72-4.87) and condom use during intercourse among adolescents of Dutch ethnicity (OR 3.59, 95% CI 1.71-7.55) not replicated in the E-health4Uth and consultation group. The E-health4Uth and consultation intervention showed minor positive results in the mental health status of adolescents (SDQ: B=-0.60, 95% CI -1.17 to -0.04), but a negative effect on drug use among boys (OR 0.36, 95% CI 0.13-0.96). In the subgroup of adolescents who were at risk of mental health problems at baseline (and referred for a consultation with the nurse), the E-health4Uth and consultation group showed minor to moderate positive results in mental health status (SDQ: B=-1.79, 95% CI -3.35 to -0.22; YSR: B=-9.11, 95% CI -17.52 to -0.71) and health-related quality of life (B=7.81, 95% CI 2.41-13.21) at follow-up compared to adolescents in the control group who were at risk of mental health problems at baseline.
conclusionsFindings from this study support the use of the E-health4Uth and consultation intervention in promoting the well-being of adolescents at risk of mental health problems. Future research is needed to further evaluate the effects of the consultation as a standalone intervention, and the dual approach of further tailored eHealth messages and a consultation.
trial registrationNederlands Trial Register: NTR 3596; http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=3596 (Archived by WebCite at http://www.webcitation.org/6PmgrPOuv).
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