ReviewFrontiers in neuroendocrinology2014
Epigenetic regulation of estrogen-dependent memory.
Review in Frontiers in neuroendocrinology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 62 citations in OpenAlex.
- Effects of cannabidiol in comparison to hormonal therapy on estrogen decline-induced memory impairments and endocannabinoid system in rats.Journal of neuroendocrinology · 2026Article
- Chronic Alcohol Drinking Impairs Recognition Memory And Insulin-Associated Genes In The Medial Prefrontal Cortex.Molecular neurobiology · 2025Article
- Connecting the Dots: Potential Interactions Between Sex Hormones and the Circadian System During Memory Consolidation.Journal of biological rhythms · 2023Article
- The Pathological Effects of Circulating Hydrophobic Bile Acids in Alzheimer's Disease.Journal of Alzheimer's disease reports · 2023Review
- Neuromodulating roles of estrogen and phytoestrogens in cognitive therapeutics through epigenetic modifications during aging.Frontiers in aging neuroscience · 2022Review
- Metabolic and Epigenetic Regulation by Estrogen in Adipocytes.Frontiers in endocrinology · 2022Review
- The scientific body of knowledge - Whose body does it serve? A spotlight on oral contraceptives and women's health factors in neuroimaging.Frontiers in neuroendocrinology · 2021Review
- Estrogenic regulation of memory: The first 50 years.Hormones and behavior · 2020Review
- Epigenetic mechanisms underlying the effects of triptolide and tripchlorolide on the expression of neuroligin-1 in the hippocampus of APP/PS1 transgenic mice.Pharmaceutical biology · 2019Article
- Sex differences and the neurobiology of affective disorders.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2019Review
- Cyto-nuclear shuttling of afadin is required for rapid estradiol-mediated modifications of histone H3.Neuropharmacology · 2018Article
- Estradiol and hippocampal memory in female and male rodents.Current opinion in behavioral sciences · 2018Article
- The Middle-Aged Brain: Biological sex and sex hormones shape memory circuitry.Current opinion in behavioral sciences · 2018Article
- Differential control of appetitive and consummatory sexual behavior by neuroestrogens in male quail.Hormones and behavior · 2018Review
- Estrogenic regulation of memory consolidation: A look beyond the hippocampus, ovaries, and females.Physiology & behavior · 2018Review
- Sex steroid hormones and brain function: PET imaging as a tool for research.Journal of neuroendocrinology · 2018Review
- Rapid actions of oestrogens and their receptors on memory acquisition and consolidation in females.Journal of neuroendocrinology · 2018Review
- Why estrogens matter for behavior and brain health.Neuroscience and biobehavioral reviews · 2017Review
- Impact of Sex and Menopausal Status on Episodic Memory Circuitry in Early Midlife.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Can Exercise Ameliorate Aromatase Inhibitor-Induced Cognitive Decline in Breast Cancer Patients?Molecular neurobiology · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Hippocampal memory formation is highly regulated by post-translational histone modifications and DNA methylation. Accordingly, these epigenetic processes play a major role in the effects of modulatory factors, such as sex steroid hormones, on hippocampal memory. Our laboratory recently demonstrated that the ability of the potent estrogen 17β-estradiol (E2) to enhance hippocampal-dependent novel object recognition memory in ovariectomized female mice requires ERK-dependent histone H3 acetylation and DNA methylation in the dorsal hippocampus. Although these data provide valuable insight into the chromatin modifications that mediate the memory-enhancing effects of E2, epigenetic regulation of gene expression is enormously complex. Therefore, more research is needed to fully understand how E2 and other hormones employ epigenetic alterations to shape behavior. This review discusses the epigenetic alterations shown thus far to regulate hippocampal memory, briefly reviews the effects of E2 on hippocampal function, and describes in detail our work on epigenetic regulation of estrogenic memory enhancement.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.