Evidence map›Paper›PMID 24877157›Full record

ReviewJournal of immunology research2014

The role of dendritic cells in tissue-specific autoimmunity.

Jacques Mbongue, Dequina Nicholas, Anthony Firek, William Langridge

Open access · goldAbstract readReview
In one paragraph

Review in Journal of immunology research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 86 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. The Integrated Cellular and Molecular Landscape of Autoimmunity.bioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. Review
  7. Vaccines · 2025
    Review
  8. T Cell Development: From T-Lineage Specification to Intrathymic Maturation.Advances in experimental medicine and biology · 2025
    Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. The Delivery of mRNA Vaccines for Therapeutics.Life (Basel, Switzerland) · 2022
    Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jacques MbongueCenter for Health Disparities and Molecular Medicine, 11085 Campus Street, Mortensen Hall, Department of Basic Sciences, Loma Linda University School of Medicine, Loma Linda, CA 92354, USA.ORCID 0000-0002-7123-3480
Dequina NicholasCenter for Health Disparities and Molecular Medicine, 11085 Campus Street, Mortensen Hall, Department of Basic Sciences, Loma Linda University School of Medicine, Loma Linda, CA 92354, USA.ORCID 0000-0003-4996-2190
Anthony FirekEndocrinology Section, JL Pettis Memorial VA Medical Center, Loma Linda, CA 92354, USA.ORCID 0000-0003-4433-1349
William LangridgeCenter for Health Disparities and Molecular Medicine, 11085 Campus Street, Mortensen Hall, Department of Basic Sciences, Loma Linda University School of Medicine, Loma Linda, CA 92354, USA.
Loma Linda University · USJerry L. Pettis Memorial VA Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this review, we explore the role of dendritic cell subsets in the development of tissue-specific autoimmune diseases. From the increasing list of dendritic cell subclasses, it is becoming clear that we are only at the beginning of understanding the role of these antigen presenting cells in mediating autoimmunity. Emerging research areas for the study of dendritic cell involvement in the onset and inhibition of tissue-specific autoimmunity are presented. Further, we compare tissue specific to systemic autoimmunity to demonstrate how development of dendritic cell-based therapies may be broadly applicable to both classes of autoimmunity. Continued development of these research areas will lead us closer to clinical assessment of novel immunosuppressive therapy for the reversal and prevention of tissue-specific autoimmunity. Through description of dendritic cell functions in the modulation of tissue-specific autoimmunity, we hope to stimulate a greater appreciation and understanding of the role dendritic cells play in the development and treatment of autoimmunity.

Indexed as

AutoimmunityAdaptive ImmunityAutoimmune DiseasesCell- and Tissue-Based TherapyCell LineageDendritic CellsGenetic TherapyHumansImmunity, InnateImmunologic FactorsOrgan SpecificityImmunologic Factors

Identifiers

PMID24877157
PMCPMC4022068
OpenAlexW1995127953

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.