Evidence map›Paper›PMID 24877073›Full record

SynthesisBioMed research international2014

Synchronous and metachronous breast malignancies: a cross-sectional retrospective study and review of the literature.

Ambrogio P Londero, Sergio Bernardi, Serena Bertozzi, Vito Angione, Giuliana Gentile, Cinzia Dri, Antonio Minucci, Filippo Caponnetto, Roberto Petri

Open access · hybridAbstract readMeta-Analysis
In one paragraph

Synthesis in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Observational
  12. Article
  13. Article
  14. A rare case of bilateral breast lobular carcinoma coexisting with primary breast follicular lymphoma.Journal of community hospital internal medicine perspectives · 2019
    Article
  15. Article
  16. Article
  17. Article
  18. Synchronous Bilateral Breast Cancers.Journal of clinical and diagnostic research : JCDR · 2015
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ambrogio P LonderoClinic of Obstetrics and Gynecology, University of Udine, 33100 Udine, Italy.
Sergio BernardiDepartment of Surgery, AOU "SM della Misericordia," 33100 Udine, Italy.
Serena BertozziDepartment of Surgery, AOU "SM della Misericordia," 33100 Udine, Italy.
Vito AngioneDepartment of Pathology, AOU "SM della Misericordia," 33100 Udine, Italy.
Giuliana GentileDepartment of Surgery, AOU "SM della Misericordia," 33100 Udine, Italy.
Cinzia DriDepartment of Surgery, AOU "SM della Misericordia," 33100 Udine, Italy.
Antonio MinucciDepartment of Surgery, AOU "SM della Misericordia," 33100 Udine, Italy.
Filippo CaponnettoDepartment of Surgery, AOU "SM della Misericordia," 33100 Udine, Italy.
Roberto PetriDepartment of Surgery, AOU "SM della Misericordia," 33100 Udine, Italy.
Ospedale Santa Maria della Misericordia di Udine · ITUniversity of Udine · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThere is increasing interest in patients with metachronous (MBC) and synchronous breast cancer (SBC). The objective of this study was to evaluate the occurrence and outcome of MBCs and SBCs.

methodsA retrospective study on women operated in our department for breast cancer between 2002 and 2005 was carried out. Patients were divided into three groups: women with MBC, SBC, and unilateral breast cancer (UBC). Moreover, we performed a meta-analysis of the English literature about multiple breast cancers between 2000 and 2011 taking into consideration their prevalence and overall survival (OS).

resultsWe identified 584 breast cancer patients: 16 women (3%) presented SBC and 40 MBC (7%, second cancer after 72-month follow-up IQR 40-145). Although the meta-analysis showed significant OS differences between MBC or SBC and UBC, we did not observe any significant OS difference among the three groups of our population. Anyway, we found a significant worse disease-free survival in MBC than UBC and a significant higher prevalence of radical surgery in MBC and SBC than UBC.

conclusionsDespite the low prevalence of MBC and SBC, the presence of a long time risk of MBC confirms the crucial role of ipsi- and contralateral mammographies in the postoperative follow-up.

Indexed as

Breast NeoplasmsCross-Sectional StudiesDisease-Free SurvivalFemaleFollow-Up StudiesHumansRandomized Controlled Trials as TopicRetrospective StudiesReview Literature as TopicSurvival Rate

Identifiers

PMID24877073
PMCPMC4022260
OpenAlexW2022789603

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.