Evidence map›Paper›PMID 24877071›Full record

ArticleBioMed research international2014

Phenotypic and genotypic characterization of enterotoxigenic Escherichia coli clinical isolates from northern Colombia, South America.

Julio A Guerra, Yesenia C Romero-Herazo, Octavio Arzuza, Oscar G Gómez-Duarte

Abstract read
In one paragraph

Article in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Epidemiology of enterotoxigenicFrontiers in public health · 2024
    Article
  3. Colonizing and Virulence Factors in Enterotoxigenic Escherichia coli from Peru.The American journal of tropical medicine and hygiene · 2023
    Article
  4. Article
  5. Article
  6. Pathogens (Basel, Switzerland) · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. [Acute diarrheal disease caused by enteropathogenic Escherichia coli in Colombia].Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Julio A GuerraDivision of Pediatric Infectious Diseases, Vanderbilt University School of Medicine, 1161 21st Avenue South, Nashville, TN 37232-2581, USA.
Yesenia C Romero-HerazoDivision of Pediatric Infectious Diseases, Vanderbilt University School of Medicine, 1161 21st Avenue South, Nashville, TN 37232-2581, USA.
Octavio ArzuzaDepartamento de Microbiología, Grupo de Microbiología Clínica y Ambiental, Universidad de Cartagena, Cartagena, Colombia.
Oscar G Gómez-DuarteDivision of Pediatric Infectious Diseases, Vanderbilt University School of Medicine, 1161 21st Avenue South, Nashville, TN 37232-2581, USA.

Funding

Studies on Emergent Diarrheagenic E. coli PathogensR01AI095346 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GOMEZ, OSCAR G · 2013 to 2017
$1.9M
NIAID NIH HHS R01 AI095346NIAID NIH HHS R01AI095346
6 · The paper itself

Abstract

Enterotoxigenic Escherichia coli (ETEC) are major causes of childhood diarrhea in low and middle income countries including Colombia, South America. To understand the diversity of ETEC strains in the region, clinical isolates obtained from northern Colombia children were evaluated for multiple locus sequencing typing, serotyping, classical and nonclassical virulence genes, and antibiotic susceptibility. Among 40 ETEC clinical isolates evaluated, 21 (52.5%) were positive for LT gene, 13 (32.5%) for ST gene, and 6 (15%) for both ST and LT. The most prevalent colonization surface antigens (CS) were CS21 and CFA/I identified in 21 (50%) and 13 (32.5%) isolates, respectively. The eatA, irp2, and fyuA were the most common nonclassical virulence genes present in more than 60% of the isolates. Ampicillin resistance (80% of the strains) was the most frequent phenotype among ETEC strains followed by trimethoprim-sulfamethoxazole resistance (52.5%). Based on multiple locus sequencing typing (MLST), we recognize that 6 clonal groups of ETEC clinical isolates circulate in Colombia. ETEC clinical isolates from children in northern Colombia are highly diverse, yet some isolates circulating in the community belong to well-defined clonal groups that share a unique set of virulence factors, serotypes, and MLST sequence types.

Indexed as

GenotypeAmpicillin ResistanceBacterial ToxinsCarrier ProteinsChildChild, PreschoolColombiaEnterotoxigenic Escherichia coliEscherichia coli InfectionsEscherichia coli ProteinsFemaleHigh-Throughput Nucleotide SequencingHumansInfantInfant, NewbornMaleBacterial ToxinsCarrier ProteinsEatA protein, E coliEscherichia coli ProteinsFyuA protein, E coliPeptide HydrolasesReceptors, Cell Surface

Identifiers

PMID24877071
PMCPMC4022111

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.