Evidence map›Paper›PMID 24876700›Full record

ArticleJournal of international oral health : JIOH2014

Serum lipid profile in oral precancer and cancer: a diagnostic or prognostic marker?

Deepanshu Garg, M K Sunil, Param Pal Singh, Neetu Singla, S R Ashwini Rani, Beant Kaur

Open access · greenAbstract read
In one paragraph

Article in Journal of international oral health : JIOH, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
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  7. Plasma Metabolic Phenotypes of HPV-Associated versus Smoking-Associated Head and Neck Cancer and Patient Survival.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Deepanshu GargDepartment of Oral Medicine & Radiology, Guru Nanak Dev Dental College and Research Institute, Sunam, Punjab, India.
M K SunilDepartment of Oral Medicine & Radiology, Guru Nanak Dev Dental College and Research Institute, Sunam, Punjab, India.
Param Pal SinghDepartment of Oral Medicine & Radiology, Guru Nanak Dev Dental College and Research Institute, Sunam, Punjab, India.
Neetu SinglaDepartment of Oral Medicine & Radiology, Guru Nanak Dev Dental College and Research Institute, Sunam, Punjab, India.
S R Ashwini RaniDepartment of Oral Medicine & Radiology, School of Dental Sciences, KIMSDU, Maharashtra, India.
Beant KaurDepartment of Oral Medicine & Radiology, Guru Nanak Dev Dental College and Research Institute, Sunam, Punjab, India.
Guru Nanak Dev University · INKrishna Institute of Medical Sciences Deemed University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChanges in lipid profile have been associated with malignancy because of their key role in the maintenance the integrity of the cell membrane. This study evaluated the alterations in serum lipid profile in untreated patients of oral submucus fibrosis (OSMF), oral leukoplakia, and oral lichen planus and proven cases of oral cancer with respect to healthy controls. MATERIALS &

methodsIn this case control study, 20 clinically and histopathologically proven patients of oral precancer and oral cancer each were compared with 20 healthy controls. In these groups, serumlipids including: (i) Total cholesterol. (ii) Triglycerides (TGL). (iii) High density lipoprotein cholesterol (HDL), low density lipoprotein cholesterol (LDL) and very low density lipoprotein cholesterol (VLDL) were analyzed.

resultsDecrease in plasma total cholesterol, triglycerides, HDL, LDL, VLDL in the subjects with the oral precancer and oral cancer as compared to the controls was statistically significant. There was also decrease in plasma levels of TGL and VLDL in oral cancer subjects as compared to precancer subjects. Thus, it was found that there is an inverse relationship between plasma lipid levels and patients.

conclusionPost operative morbidity was increasing along with more operating time and increase in the depth of mandibular third molar impaction. How to cite the article: Garg D, Sunil MK, Singh PP, Singla N, Rani SR, Kaur B. Serum lipid profile in oral precancer and cancer: a diagnostic or prognostic marker? J Int Oral Health 2014;6(2):33-9.

Indexed as

head cancerleukoplakialichen planuslipid profileneck canceroral submucus fibrosis

Identifiers

PMID24876700
PMCPMC4037787
OpenAlexW2993104815

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.