Evidence map›Paper›PMID 24876548›Full record

ArticleJournal of diabetes science and technology2014

Comparative Assessment of Lixisenatide, Exenatide, and Liraglutide Pen Devices: A Pilot User-Based Study.

Udo Stauder, Diplom Enginee, Hina Elton, Alfred Penfornis, Steve Edelman

Open access · bronzeAbstract read
In one paragraph

Article in Journal of diabetes science and technology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. National Poison Center Trends in GLP-1 Receptor Agonist Exposures Following FDA Approval for Weight Loss.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2026
    Article
  2. GLP-1 Receptor Agonist Exposures Are Increasingly Common and Generally Associated with Mild Symptoms: A Single Poison Center Experience.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2024
    Article
  3. Article
  4. Article
  5. A Review of Practical Issues on the Use of Glucagon-Like Peptide-1 Receptor Agonists for the Management of Type 2 Diabetes.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2019
    Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 4 countries.

Udo StauderSanofi-Aventis, Frankfurt, Germany DCA Design International, Warwick, UK Jean Minjoz Hospital, Besançon, France University of California, San Diego, San Diego, CA, USA Udo.Stauder@sanofi.com.
Diplom EngineeSanofi-Aventis, Frankfurt, Germany.
Hina EltonDCA Design International, Warwick, UK.
Alfred PenfornisJean Minjoz Hospital, Besançon, France.
Steve EdelmanUniversity of California, San Diego, San Diego, CA, USA.
DCA (United Kingdom) · GBHôpital Privé Jean Mermo · FRSanofi (France) · FRSanofi (Germany) · DEUniversity of California, San Diego · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGlucagon-like peptide-1 (GLP-1) receptor agonists are a relatively recent addition to the treatment options for type 2 diabetes mellitus (T2DM) and are administered using prefilled pen devices.

methodIn this open-label task and interview-based pilot study, 3 GLP-1 receptor agonist pen devices-exenatide (Byetta

resultsTasks were completed faster (P < .001) and with higher successful performance (P = .001) with the lixisenatide pen than with the exenatide pen, whereas the liraglutide pen was not statistically significant versus the exenatide pen on these parameters. Overall, user satisfaction was statistically higher for the lixisenatide and liraglutide pens versus the exenatide pen (P < .001 for both).

conclusionsLixisenatide and liraglutide pens are associated with higher user satisfaction compared with the exenatide pen. In addition, the lixisenatide pen is faster and results in fewer errors than its comparator (exenatide). The lixisenatide pen may therefore be a suitable choice for patients with T2DM, including older and pen device-naïve patients, and those with visual impairments and reduced manual dexterity.

Indexed as

ease of useglucagon-like peptide-1 receptor agonistslixisenatideprefilled pen devicestype 2 diabetes mellitus

Identifiers

PMID24876548
PMCPMC4454110
OpenAlexW2105000105

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.