Evidence map›Paper›PMID 24876449›Full record

ArticleJournal of diabetes science and technology2014

Effect of whole body vibration on skin blood flow and nitric oxide production.

Paula K Johnson, J Brent Feland, A Wayne Johnson, Gary W Mack, Ulrike H Mitchell

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of diabetes science and technology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 3 pooled it
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 3 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. Pooled it
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  10. Effect of mechanical vibration on peripheral blood flow in laboratory exposure: a narrative review.International journal of occupational medicine and environmental health · 2026
    Review
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  13. Article
  14. Article
  15. Article
  16. Article
  17. Effect of Whole-Body Vibration Training on Hemorheological Blood Indices in Young, Healthy Women.International journal of environmental research and public health · 2023
    Article
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  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Paula K JohnsonDepartment of Exercise Sciences, Brigham Young University, Provo, UT, USA paula.v.johnson@byu.edu.
J Brent FelandDepartment of Exercise Sciences, Brigham Young University, Provo, UT, USA.
A Wayne JohnsonDepartment of Exercise Sciences, Brigham Young University, Provo, UT, USA.
Gary W MackDepartment of Exercise Sciences, Brigham Young University, Provo, UT, USA.
Ulrike H MitchellDepartment of Exercise Sciences, Brigham Young University, Provo, UT, USA.
Brigham Young University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVascular dysfunction due to hyperglycemia in individuals with diabetes is a factor contributing to distal symmetric polyneuropathy (DSPN). Reactive oxygen species reduce the bioavailability of nitric oxide (NO), a powerful vasodilator, resulting in reduced circulation and nerve ischemia. Increases in blood NO concentrations and circulation have been attributed to whole body vibration (WBV). The purpose of this study was to the determine the effects of low-frequency, low-amplitude WBV on whole blood NO concentrations and skin blood flow (SBF) in individuals with symptoms of DSPN.

methodsTen patients with diabetes and impaired sensory perception in the lower limbs participated in this crossover study. Each submitted to 2 treatment conditions, WBV and sham, with a 1-week washout period between. Blood draws for NO analysis and laser Doppler imager scans of SBF were performed before, immediately after, and following a 5-minute recovery of each of the treatments.

resultsLow-frequency, low-amplitude WBV significantly increased SBF compared to the sham condition (F(2,18) = 5.82, P = .0115). Whole blood NO concentrations did not differ between the WBV and sham conditions immediately or 5 minutes after treatment (F(2,18) = 1.88, P = .1813).

conclusionsThese findings demonstrate that patients with diabetes respond to WBV with increased SBF compared to the sham condition. The implication is that WBV is a potential nonpharmacological therapy for neurovascular complications of diabetes.

Indexed as

AgedAged, 80 and overCross-Over StudiesCross-Sectional StudiesDiabetes MellitusDiabetic NeuropathiesFemaleHumansMaleMiddle AgedNitric OxideRegional Blood FlowSkinVibrationNitric Oxidediabetesneuropathynitric oxideskin blood flowwhole body vibration

Identifiers

PMID24876449
PMCPMC4764225
OpenAlexW2099483078

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.