Evidence map›Paper›PMID 24876425›Full record

ArticleJournal of diabetes science and technology2014

Evaluation of the utility of a glycemic pattern identification system.

Erik A Otto, Vinay Tannan

2 registry-linked trialsAbstract read
In one paragraph

Article in Journal of diabetes science and technology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02682940 naterminatednot on this mapstarted 2016, after this paper: background citation

Type I Diabetes Hypoglycemia Prevention Pilot Study

TypeinterventionalSponsorInSpark Technologies, Inc.Ran2016 to 2016Enrolled4ConditionsDiabetes Mellitus, Type 1, HypoglycemiaArmsVigilant Diabetes Management Application
NCT02906891 naterminatednot on this mapstarted 2016, after this paper: background citation

A Pilot Study of Nocturnal Hypoglycemia Prevention in Type 1 Diabetes Using the Vigilant Diabetes Management Companion

TypeinterventionalSponsorInSpark Technologies, Inc.Ran2016 to 2016Enrolled13ConditionsHypoglycemia, Diabetes Mellitus, Type 1ArmsVigilant Diabetes Management Application
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Erik A OttoInSpark Technologies, Inc, Charlottesville, VA, USA eotto@insparktech.com.
Vinay TannanTaan Consulting LLC, Charlottesville, VA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWith the increasing prevalence of systems allowing automated, real-time transmission of blood glucose data there is a need for pattern recognition techniques that can inform of deleterious patterns in glycemic control when people test. We evaluated the utility of pattern identification with a novel pattern identification system named Vigilant™ and compared it to standard pattern identification methods in diabetes.

methodTo characterize the importance of an identified pattern we evaluated the relative risk of future hypoglycemic and hyperglycemic events in diurnal periods following identification of a pattern in a data set of 536 patients with diabetes. We evaluated events 2 days, 7 days, 30 days, and 61-90 days from pattern identification, across diabetes types and cohorts of glycemic control, and also compared the system to 6 pattern identification methods consisting of deleterious event counts and percentages over 5-, 14-, and 30-day windows.

resultsEpisodes of hypoglycemia, hyperglycemia, severe hypoglycemia, and severe hyperglycemia were 120%, 46%, 123%, and 76% more likely after pattern identification, respectively, compared to periods when no pattern was identified. The system was also significantly more predictive of deleterious events than other pattern identification methods evaluated, and was persistently predictive up to 3 months after pattern identification.

conclusionsThe system identified patterns that are significantly predictive of deleterious glycemic events, and more so relative to many pattern identification methods used in diabetes management today. Further study will inform how improved pattern identification can lead to improved glycemic control.

Indexed as

Pattern Recognition, AutomatedArea Under CurveBenchmarkingBlood GlucoseCircadian RhythmCohort StudiesDiabetes MellitusHumansHyperglycemiaHypoglycemiaPredictive Value of TestsRisk AssessmentBlood Glucoseanalysisblooddiabetesglucoseidentificationpattern

Identifiers

PMID24876425
PMCPMC4764210

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.