Evidence map›Paper›PMID 24876255›Full record

ArticleThe Plant cell2014

Large-Scale Proteomics of the Cassava Storage Root and Identification of a Target Gene to Reduce Postharvest Deterioration.

Hervé Vanderschuren, Evans Nyaboga, Jacquelyne S Poon, Katja Baerenfaller, Jonas Grossmann, Matthias Hirsch-Hoffmann, Norbert Kirchgessner, Paolo Nanni, Wilhelm Gruissem

Open access · bronzeAbstract read
In one paragraph

Article in The Plant cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 107 citations in OpenAlex.

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  13. Feeding Value Assessment of Substituting Cassava (Animals : an open access journal from MDPI · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Hervé VanderschurenDepartment of Biology, ETH Zurich, 8092 Zurich, Switzerland hvanderschuren@ethz.ch.ORCID http://orcid.org/0000-0003-2102-9737
Evans NyabogaDepartment of Biology, ETH Zurich, 8092 Zurich, Switzerland.
Jacquelyne S PoonDepartment of Biology, ETH Zurich, 8092 Zurich, Switzerland.
Katja BaerenfallerDepartment of Biology, ETH Zurich, 8092 Zurich, Switzerland.ORCID http://orcid.org/0000-0002-1904-9440
Jonas GrossmannFunctional Genomics Center Zurich, UZH/ETH, 8057 Zurich, Switzerland.
Matthias Hirsch-HoffmannDepartment of Biology, ETH Zurich, 8092 Zurich, Switzerland.
Norbert KirchgessnerInstitute of Agricultural Sciences, ETH Zurich, 8092 Zurich, Switzerland.
Paolo NanniFunctional Genomics Center Zurich, UZH/ETH, 8057 Zurich, Switzerland.
Wilhelm GruissemDepartment of Biology, ETH Zurich, 8092 Zurich, Switzerland.
ETH Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cassava (Manihot esculenta) is the most important root crop in the tropics, but rapid postharvest physiological deterioration (PPD) of the root is a major constraint to commercial cassava production. We established a reliable method for image-based PPD symptom quantification and used label-free quantitative proteomics to generate an extensive cassava root and PPD proteome. Over 2600 unique proteins were identified in the cassava root, and nearly 300 proteins showed significant abundance regulation during PPD. We identified protein abundance modulation in pathways associated with oxidative stress, phenylpropanoid biosynthesis (including scopoletin), the glutathione cycle, fatty acid α-oxidation, folate transformation, and the sulfate reduction II pathway. Increasing protein abundances and enzymatic activities of glutathione-associated enzymes, including glutathione reductases, glutaredoxins, and glutathione S-transferases, indicated a key role for ascorbate/glutathione cycles. Based on combined proteomics data, enzymatic activities, and lipid peroxidation assays, we identified glutathione peroxidase as a candidate for reducing PPD. Transgenic cassava overexpressing a cytosolic glutathione peroxidase in storage roots showed delayed PPD and reduced lipid peroxidation as well as decreased H

Identifiers

PMID24876255
PMCPMC4079358
OpenAlexW2119742773

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.