Evidence map›Paper›PMID 24875845›Full record

ArticleNano letters2014

Changes in the morphology and proliferation of astrocytes induced by two modalities of chemically functionalized single-walled carbon nanotubes are differentially mediated by glial fibrillary acidic protein.

Manoj K Gottipati, Elena Bekyarova, Michael Brenner, Robert C Haddon, Vladimir Parpura

Open access · bronzeAbstract read
In one paragraph

Article in Nano letters, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Manoj K GottipatiDepartment of Neurobiology, University of Alabama , Birmingham, Alabama 35294, United States.
Elena Bekyarova
Michael Brenner
Robert C Haddon
Vladimir Parpura
University of Alabama at Birmingham · USUniversity of California, Riverside · US

Funding

The Role of Astroglia in the Enteric Nervous System and Gut FunctionR21HD078678 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI PARPURA, VLADIMIR · 2014 to 2015
$400k
NICHD NIH HHS HD078678NICHD NIH HHS R21 HD078678
6 · The paper itself

Abstract

Alterations in glial fibrillary acidic protein (GFAP) levels accompany the changes in the morphology and proliferation of astrocytes induced by colloidal solutes and films of carbon nanotubes (CNTs). To determine if GFAP is required for the effects of CNTs on astrocytes, we used astrocytes isolated from GFAP null mice. We find that selected astrocytic changes induced by CNTs are mediated by GFAP, i.e., perimeter, shape, and cell death for solutes, and proliferation for films.

Indexed as

AnimalsAstrocytesCell ProliferationCells, CulturedCell ShapeGlial Fibrillary Acidic ProteinMice, Inbred C57BLMice, KnockoutNanotubes, CarbonGlial Fibrillary Acidic ProteinNanotubes, Carbon

Identifiers

PMID24875845
PMCPMC4091642
OpenAlexW2315188211

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.