Evidence map›Paper›PMID 24875787›Full record

ArticleInternational journal of neural systems2014

Simulating vertical and horizontal inhibition with short-term dynamics in a multi-column multi-layer model of neocortex.

Beata Strack, Kimberle M Jacobs, Krzysztof J Cios

Abstract read
In one paragraph

Article in International journal of neural systems, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Beata StrackDepartment of Computer Science, Virginia Commonwealth University, Richmond, VA, USA.
Kimberle M Jacobs
Krzysztof J Cios

Funding

Role of Interneuron Subtypes in Malformed CortexR01NS054210 · NINDS · VIRGINIA COMMONWEALTH UNIVERSITY · PI JACOBS, KIMBERLE MAE · 2008 to 2018
$3.0M
NINDS NIH HHS R01 NS054210
6 · The paper itself

Abstract

The paper introduces a multi-layer multi-column model of the cortex that uses four different neuron types and short-term plasticity dynamics. It was designed with details of neuronal connectivity available in the literature and meets these conditions: (1) biologically accurate laminar and columnar flows of activity, (2) normal function of low-threshold spiking and fast spiking neurons, and (3) ability to generate different stages of epileptiform activity. With these characteristics the model allows for modeling lesioned or malformed cortex, i.e. examine properties of developmentally malformed cortex in which the balance between inhibitory neuron subtypes is disturbed.

Indexed as

Computer SimulationLeukemia, Myeloid, AcuteModels, NeurologicalAction PotentialsAnimalsHumansNeocortexNeural InhibitionNeurons

Identifiers

PMID24875787
PMCPMC9422346

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.