ArticleBehavioural brain research2014
Maintenance of dominance status is necessary for resistance to social defeat stress in Syrian hamsters.
Article in Behavioural brain research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 42 citations in OpenAlex.
- Dichotomous Regulation of Social Behaviors by Nucleus Accumbens Neurons in Female and Male Syrian Hamsters.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Involvement of the central amygdaloid nucleus in the regulation of sex differences in the stress relief response in mice.Biology of sex differences · 2026Article
- Distinct subcircuits within the mesolimbic dopamine system encode the salience and valence of social stimuli.Psychopharmacology · 2025Article
- Distinguishing neural ensembles in the infralimbic cortex that regulate stress vulnerability and coping behavior.Neurobiology of stress · 2025Article
- Article
- Effects of social dominance and acute social stress on morphology of microglia and structural integrity of the medial prefrontal cortex.Brain, behavior, and immunity · 2024Article
- Activation of androgen receptor-expressing neurons in the posterior medial amygdala is associated with stress resistance in dominant male hamsters.Hormones and behavior · 2024Article
- Social status predicts physiological and behavioral responses to chronic stress in rhesus monkeys.iScience · 2024Article
- Sex influences the effects of social status on socioemotional behavior and serotonin neurochemistry in rhesus monkeys.Biology of sex differences · 2023Article
- Sex differences in dominance relationships in Syrian hamsters.Physiology & behavior · 2023Article
- Dominance status modulates activity in medial amygdala cells with projections to the bed nucleus of the stria terminalis.Behavioural brain research · 2023Article
- Sex and social status modify the effects of fluoxetine on socioemotional behaviors in Syrian hamsters and rhesus macaques.Pharmacology, biochemistry, and behavior · 2022Article
- Manifestations of domination: Assessments of social dominance in rodents.Genes, brain, and behavior · 2022Review
- Individual history of winning and hierarchy landscape influence stress susceptibility in mice.eLife · 2021Article
- Gonadal steroid hormone receptors in the medial amygdala contribute to experience-dependent changes in stress vulnerability.Psychoneuroendocrinology · 2021Article
- Using social rank as the lens to focus on the neural circuitry driving stress coping styles.Current opinion in neurobiology · 2021Review
- Chemogenetic activation of an infralimbic cortex to basolateral amygdala projection promotes resistance to acute social defeat stress.Scientific reports · 2020Article
- Social experience and sex-dependent regulation of aggression in the lateral septum by extrasynaptic δGABAPsychopharmacology · 2020Article
- Effect of Aggressive Experience in Female Syrian Hamsters on Glutamate Receptor Expression in the Nucleus Accumbens.Frontiers in behavioral neuroscience · 2020Article
- Activity of a vmPFC-DRN Pathway Corresponds With Resistance to Acute Social Defeat Stress.Frontiers in neural circuits · 2020Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Resilience is an active process that involves a discrete set of neural substrates and cellular mechanisms and enables individuals to avoid some of the negative consequences of extreme stress. We have previously shown that dominant individuals show less stress-induced changes in behavior compared to subordinates using a conditioned defeat model in male Syrian hamsters (Mesocricetus auratus). To rule out pre-existing differences between dominants and subordinates, we examined whether 14 days of dominance experience is required to reduce the conditioned defeat response and whether the development of conditioned defeat resistance correlates with defeat-induced neural activation in select brain regions. We paired hamsters in daily 5-min aggressive encounters for 1, 7, or 14 days and then exposed animals to 3, 5-min social defeat episodes. The next day animals received conditioned defeat testing which involved a 5-min social interaction test with a non-aggressive intruder. In separate animals brains were collected after social defeat for c-Fos immunohistochemistry. We found that 14-day dominants showed a decreased conditioned defeat response compared to 14-day subordinates and controls, while 1-day and 7-day dominants did not differ from their subordinate counterparts. Also, the duration of dominance relationship was associated with distinct patterns of defeat-induced neural activation such that only 14-day dominants showed elevated c-Fos immunoreactivity in the ventral medial prefrontal cortex, medial amygdala, and lateral portions of the ventral medial hypothalamus. Our data suggest that resistance to social stress develops during the maintenance of dominance relationships and is associated with experience-dependent neural plasticity in select brain regions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.