ArticleDeutsches Arzteblatt international2014
The reduction of nosocomial MRSA infection in Germany: an analysis of data from the Hospital Infection Surveillance System (KISS) between 2007 and 2012.
Article in Deutsches Arzteblatt international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Individual and institutional predisposing factors of MRSA surgical site infection and outcomes-a retrospective case-control-study in 14 European high-volume surgical centres.JAC-antimicrobial resistance · 2024Article
- Molecular Assessment of Staphylococcus Aureus Strains in STAT3 Hyper-IgE Syndrome Patients.Journal of clinical immunology · 2022Article
- Development and challenges in setting up an international bone infection registry.Archives of orthopaedic and trauma surgery · 2020Article
- [Infections due to multidrug-resistant pathogens : Pathogens, resistance mechanisms and established treatment options].Der Anaesthesist · 2019Review
- New Microbiological Techniques in the Diagnosis of Bloodstream Infections.Deutsches Arzteblatt international · 2018Review
- [Antibiotic stewardship : Measures for optimizing prescription of anti-infective agents].Der Anaesthesist · 2018Review
- The tigecycline evaluation and surveillance trial; assessment of the activity of tigecycline and other selected antibiotics against gram-positive and gram-negative pathogens from France collected between 2004 and 2016.Antimicrobial resistance and infection control · 2018Article
- Antimicrobial susceptibility of bacterial isolates from patients presenting with ear, nose and throat (ENT) infections in the German community healthcare setting.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2017Article
- Article
- Nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA) at a palliative care unit: A prospective single service analysis.PloS one · 2017Article
- MRSA Prevalence and Risk Factors among Health Personnel and Residents in Nursing Homes in Hamburg, Germany - A Cross-Sectional Study.PloS one · 2017Article
- Quality indicators in intensive care medicine for Germany - third edition 2017.German medical science : GMS e-journal · 2017Review
- Temporal trends of the in vitro activity of tigecycline and comparator antibiotics against clinical aerobic bacterial isolates collected in Germany, 2006-2014: results of the Tigecycline Evaluation and Surveillance Trial (TEST).GMS infectious diseases · 2016Article
- Methicillin-Resistant Staphylococcus aureus in Saarland, Germany: The Long-Term Care Facility Study.PloS one · 2016Article
- Improving hospital hygiene to reduce the impact of multidrug-resistant organisms in health care--a prospective controlled multicenter study.BMC infectious diseases · 2015Article
- Article
- Perioperative Antibiotic Prophylaxis and Antimicrobial Therapy of Intra-Abdominal Infections.Viszeralmedizin · 2014Review
- Large numbers do not make for great science.Deutsches Arzteblatt international · 2014Article
- In reply.Deutsches Arzteblatt international · 2014Article
- Different study methods.Deutsches Arzteblatt international · 2014Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInfections with multiresistant Gram negative pathogens are rising around the world, but many European countries have recently seen a decline in infections due to methicillin resistant Staphylococcus aureus (MRSA). We determined the percentage of nosocomial Staphylococcus aureus infections in Germany that were accounted for by MRSA in the past six years and looked for regional differences in the overall downward trend.
methodsData from the German Hospital Infection Surveillance System (Krankenhaus-Infektions-Surveillance-System, KISS) from the years 2007-2012 were analyzed. In intensive care units, data on the following nosocomial infections were registered: primary sepsis, lower respiratory tract infections, and urinary tract infections; in surgical wards, data on postoperative wound infections were collected.
resultsThe number of participating intensive care units varied from 465 to 645, while the number of participating surgical wards varied from 432 to 681. Over the period 2007-2012, the percentage of nosocomial Staphylococcus aureus infections that were due to MRSA dropped significantly, from 33% to 27%. More specifically, the percentage of infections due to MRSA dropped from 36% to 31% for primary sepsis and from 36% to 30% for lower respiratory tract infections. Regression analysis revealed significantly lower MRSA fractions in the German states of Brandenburg (odds ratio [OR] 0.41), Bavaria (OR 0.73), and Saxony-Anhalt (OR 0.53), with higher fractions in Berlin (OR 1.59), Mecklenburg-West Pomerania (OR 1.91), Lower Saxony (OR 1.85), and North Rhine-Westphalia (OR 1.55). There were no significant differences in the remaining German states.
conclusionIn Germany, the percentage of nosocomial Staphylococcus aureus infections due to MRSA dropped significantly over the period 2007-2012. The causes of this decline are unclear; it may have resulted from human intervention, pathogen biology, or both.
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