Evidence map›Paper›PMID 24875275›Full record

ArticlePloS one2014

Validity of diagnostic codes and prevalence of physician-diagnosed psoriasis and psoriatic arthritis in southern Sweden--a population-based register study.

Sofia Löfvendahl, Elke Theander, Åke Svensson, Katarina Steen Carlsson, Martin Englund, Ingemar F Petersson

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 3 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 3 syntheses or guidelines pooled it, 117 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Sofia LöfvendahlDepartment of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden; Epidemiology and Register Centre South, Skåne University Hospital, Lund, Sweden.
Elke TheanderDepartment of Rheumatology, Skåne University Hospital Malmö, Lund University, Malmö, Sweden.
Åke SvenssonDepartment of Dermatology, Skåne University Hospital Malmö, Lund University, Malmö, Sweden.
Katarina Steen CarlssonDepartment of Clinical Sciences, Malmö, Lund University, Skåne University Hospital Malmö, Sweden.
Martin EnglundDepartment of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden; Epidemiology and Register Centre South, Skåne University Hospital, Lund, Sweden; Clinical Epidemiology Research & Training Unit, Boston University School of Medicine, Boston, Massachusetts, United States of America.
Ingemar F PeterssonDepartment of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden; Epidemiology and Register Centre South, Skåne University Hospital, Lund, Sweden; Arthritis Research UK Primary Care Centre, Keele University, United Kingdom.
Lund University · SESkåne University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo validate diagnostic codes for psoriasis and psoriatic arthritis (PsA) and estimate physician-diagnosed prevalence of psoriasis and PsA in the Skåne region, Sweden.

methodsIn the Skåne Healthcare Register (SHR), all healthcare consultations are continuously collected for all inhabitants in the Skåne region (population 1.2 million). During 2005-2010 we identified individuals with ≥1 physician-consultations consistent with psoriasis (ICD-10). Within this group we also identified those diagnosed with PsA. We performed a validation by reviewing medical records in 100 randomly selected cases for psoriasis and psoriasis with PsA, respectively. Further, we estimated the pre- and post-validation point prevalence by December 31, 2010.

resultsWe identified 16 171 individuals (psoriasis alone: n = 13 185, psoriasis with PsA n = 2 986). The proportion of ICD-10 codes that could be confirmed by review of medical records was 81% for psoriasis and 63% for psoriasis with PsA with highest percentage of confirmed codes for cases diagnosed ≥2 occasions in specialized care. For 19% and 29% of the cases respectively it was not possible to determine diagnosis due to insufficient information. Thus, the positive predicted value (PPV) of one ICD-10 code for psoriasis and psoriasis with PsA ranged between 81-100% and 63-92%, respectively. Assuming the most conservative PPV, the post-validation prevalence was 1.23% (95% CI: 1.21-1.25) for psoriasis (with or without PsA), 1.02% (95% CI: 1.00-1.03) for psoriasis alone and 0.21% (95% CI: 0.20-0.22) for psoriasis with PsA. The post-validation prevalence of PsA in the psoriasis cohort was 17.3% (95% CI: 16.65-17.96).

conclusionsThe proportion of diagnostic codes in SHR that could be verified varied with frequency of diagnostic codes and level of care highlighting the importance of sensitivity analyses using different case ascertainment criteria. The prevalence of physician-diagnosed psoriasis and PsA confirm other population-based studies, also after adjustment due to misclassification of disease.

Indexed as

International Classification of DiseasesAdultArthritis, PsoriaticFemaleHumansMaleMiddle AgedPhysiciansPopulation SurveillancePrevalencePsoriasisRegistriesReproducibility of ResultsSweden

Identifiers

PMID24875275
PMCPMC4038520
OpenAlexW2000061875

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.