Evidence map›Paper›PMID 24874776›Full record

ReviewPhysiology & behavior2014

Advances in the neurobiological bases for food 'liking' versus 'wanting'.

D C Castro, K C Berridge

Abstract readReview
In one paragraph

Review in Physiology & behavior, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Brain-wide activity mapping reveals the somatosensory cortex as a sex-specific regulator of hedonic feeding.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  4. Ventral pallidal GABAergic neurons control hedonic feeding and obesity.bioRxiv : the preprint server for biology · 2026
    Article
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  15. Role of mesolimbic cannabinoid receptor 1 in stress-driven increases in cocaine self-administration in male rats.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
    Article
  16. Article
  17. Article
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  19. Review
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

D C CastroDepartment of Psychology, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: castrod@umich.edu.
K C BerridgeDepartment of Psychology, University of Michigan, Ann Arbor, MI 48109, USA.

Funding

Sensory Mechanisms and Disorders - Administrative SupplementT32DC000011 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Michael Thomas Roberts · 1989 to 2026
$9.5M
Affective neuroscience of taste reactivityR01MH063649 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BERRIDGE, KENT C. · 2002 to 2024
$7.8M
Cue-triggered Reward SeekingR01DA015188 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BERRIDGE, KENT C. · 2003 to 2021
$4.9M
NIDA NIH HHS DA015188NIDA NIH HHS R01 DA015188NIDCD NIH HHS T32 DC000011NIMH NIH HHS MH63649NIMH NIH HHS R01 MH063649
6 · The paper itself

Abstract

The neural basis of food sensory pleasure has become an increasingly studied topic in neuroscience and psychology. Progress has been aided by the discovery of localized brain subregions called hedonic hotspots in the early 2000s, which are able to causally amplify positive affective reactions to palatable tastes ('liking') in response to particular neurochemical or neurobiological stimulations. Those hedonic mechanisms are at least partly distinct from larger mesocorticolimbic circuitry that generates the incentive motivation to eat ('wanting'). In this review, we aim to describe findings on these brain hedonic hotspots, especially in the nucleus accumbens and ventral pallidum, and discuss their role in generating food pleasure and appetite.

Indexed as

MotivationNeurobiologyAnimalsBrainEatingFeeding BehaviorHumansHedonic hotspotMotivationNucleus accumbensOptogeneticsParabrachial nucleusPleasureRewardVentral pallidum

Identifiers

PMID24874776
PMCPMC4246030

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.