ArticlePlant cell reports2014
LlHSFA1, a novel heat stress transcription factor in lily (Lilium longiflorum), can interact with LlHSFA2 and enhance the thermotolerance of transgenic Arabidopsis thaliana.
Article in Plant cell reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 79 citations in OpenAlex.
- Genome-Wide Analysis of the MADS-Box Gene Family and Expression Pattern Under Abiotic Stresses inInternational journal of molecular sciences · 2026Article
- A comprehensive review of physiological and molecular responses to stress of lilies (genusHorticulture research · 2026Article
- Identification of HSF gene family and functional analysis of two HSFA1 genes with tandem repeat features in Fritillaria cirrhosa D.Don.BMC genomics · 2026Article
- PtHSF5, a HSF transcription factor from Pinellia Ternata positively regulates heat tolerance in Arabidopsis.BMC plant biology · 2025Article
- Molecular mechanism analysis of LdHSFB2a in lily thermotolerance.Stress biology · 2025Article
- LzSCL9, a Novel GRAS Transcription Factor in Lanzhou Lily (Plants (Basel, Switzerland) · 2024Article
- Research Progress on Heat Stress Response Mechanism and Control Measures in Medicinal Plants.International journal of molecular sciences · 2024Review
- Deleterious Effects of Heat Stress on the Tomato, Its Innate Responses, and Potential Preventive Strategies in the Realm of Emerging Technologies.Metabolites · 2024Review
- A LlWRKY33-LlHSFA4-LlCAT2 module confers resistance toHorticulture research · 2024Article
- The Role ofPlants (Basel, Switzerland) · 2023Article
- Enhancing heat stress tolerance in Lanzhou lily (Frontiers in plant science · 2023Article
- Genome-wide analysis of HSF family and overexpression ofFrontiers in plant science · 2023Article
- Ethylene Response Factor LlERF110 Mediates Heat Stress Response via Regulation ofInternational journal of molecular sciences · 2022Article
- Regulatory Mechanisms of Heat Stress Response and Thermomorphogenesis in Plants.Plants (Basel, Switzerland) · 2022Review
- Time-Course Transcriptomic Profiling of Floral Induction in Cultivated Strawberry.International journal of molecular sciences · 2022Article
- Small HSPs play an important role in crosstalk between HSF-HSP and ROS pathways in heat stress response through transcriptomic analysis in lilies (Lilium longiflorum).BMC plant biology · 2022Article
- The Heat Stress Transcription Factor LlHsfA4 Enhanced Basic Thermotolerance through Regulating ROS Metabolism in Lilies (International journal of molecular sciences · 2022Article
- Transcriptome and Metabolome Analyses Provide Insights into the Stomium Degeneration Mechanism in Lily.International journal of molecular sciences · 2021Article
- A Novel Heat Shock Transcription Factor (International journal of molecular sciences · 2021Article
- Transcriptional and metabolite analysis reveal a shift in fruit quality in response to calcium chloride treatment on "Kyoho" grapevine.Journal of food science and technology · 2021Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
key messageA heat stress transcription factor LlHSFA1 in lily and its relationship with LlHSFA2 was investigated, and its function in enhancing thermotolerance was confirmed by analyzing transgenic Arabidopsis thaliana overexpressed LlHSFA1. A large family of heat stress transcription factors that are involved in the heat stress response in plants can induce the expression of multiple genes related to thermotolerance including heat-shock proteins. In this study, a novel class A1 HSF named LlHSFA1 was isolated from leaves of lily (Lilium longiflorum cv. 'White Heaven') using the rapid amplification of cDNA ends technique. Analysis of the deduced amino acid sequence and construction of a phylogenetic tree showed that LlHSFA1 contained five critical domains and motifs and belonged to the A1 family of HSFs. Following the heat treatment of lily leaves, transcription of LlHSFA1 was induced to a varying extent, related to the time of measurement. The induced expression peak of LlHSFA1 occurred prior to that of LlHSFA2, during the early phase of heat stress. Following transient expression of LlHSFA1 in Nicotiana benthamiana, LlHSFA1 was found to be localized in both the nucleus and the cytoplasm. Analysis using bimolecular fluorescence complementation and a yeast two-hybrid assay demonstrated that LlHSFA1 could interact with LlHSFA2. Use of a yeast one-hybrid assay confirmed that LlHSFA1 had transcriptional activation activity. In transgenic Arabidopsis lines overexpressing LlHSFA1 under unstressed conditions, the expression of some putative target genes was up-regulated, in comparison with expression in wild-type plants, and furthermore, the thermotolerance of the transgenic lines was enhanced. Overall, LlHSFA1 was demonstrated to play an important role in the heat stress response of lily and to be a novel candidate gene for application in lily breeding, using genetic modification approaches.
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