Evidence map›Paper›PMID 24872927›Full record

ArticleJournal of traditional and complementary medicine2014

Why is Research on Herbal Medicinal Products Important and How Can We Improve Its Quality?

Olavi Pelkonen, Qihe Xu, Tai-Ping Fan

Open access · hybridAbstract read
In one paragraph

Article in Journal of traditional and complementary medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
9.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 99 citations in OpenAlex.

  1. Pooled it
  2. Effects ofPharmaceuticals (Basel, Switzerland) · 2025
    Article
  3. Review
  4. Article
  5. Review
  6. Promising Antileishmanial Activity ofMolecules (Basel, Switzerland) · 2024
    Article
  7. Article
  8. Frontiers in pharmacology · 2023
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Bioactive Components ofMolecules (Basel, Switzerland) · 2021
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Olavi PelkonenDepartment of Pharmacology and Toxicology, University of Oulu, Oulu, Finland.
Qihe XuDepartment of Renal Medicine, King's College London, London, UK.
Tai-Ping FanDepartment of Pharmacology, University of Cambridge, Cambridge, UK.
Bridge University · SSKing's College London · GBUniversity of Oulu · FI

Funding

Medical Research Council MR/J006742/1
6 · The paper itself

Abstract

Research on herbal medicinal products is increasingly published in "Western" scientific journals dedicated primarily to conventional medicines. Publications are concerned mainly not only on the issues of safety and interactions, but also on efficacy. In reviews, a recurring complaint has been a lack of quality studies. In this opinion article, we present the case of Chinese herbal medicines as an example, as they have been extensively used in the global market and increasingly studied worldwide. We analyze the potential reasons for problems and propose some ways forward. As in the case of any drug, clinical trials for safety, efficacy, and/or effectiveness are the ultimate demonstration of therapeutic usefulness of herbal products. These will only make scientific sense when the tested herbal products are authentic, standardized, and quality controlled, if good practice guidelines of evidence-based medicine are followed, and if relevant controls and outcome measures are scientifically defined. Herbal products are complex mixtures, and for such complexity, an obvious approach for mechanistic studies is network pharmacology based on omic tools and approaches, which has already begun to revolutionize the study of conventional drugs, emphasizing networks, interactions, and polypharmacological features behind the action of many drugs.

Indexed as

Herbal medicinal productsNetwork pharmacologyOmic toolsPolypharmacologyTraditional chinese herbal medicines

Identifiers

PMID24872927
PMCPMC4032837
OpenAlexW1986261486

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.