ArticleNeural plasticity2014
Abnormal baseline brain activity in patients with pulsatile tinnitus: a resting-state FMRI study.
Article in Neural plasticity, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Invariant structural and functional brain regions associated with tinnitus: A meta-analysis.PloS one · 2022Pooled it
- Whole-Brain Structural Connectivity Alterations in Chronic Subjective Tinnitus: An Exploratory Diffusion Tensor Imaging Study.Brain sciences · 2026Article
- Distinct changes in the morphology of cortical and subcortical grey matter associated with age-related hearing loss and tinnitus in the UK Biobank participants.Brain communications · 2025Article
- Disruptions of default mode network and precuneus connectivity associated with cognitive dysfunctions in tinnitus.Scientific reports · 2023Article
- Altered cerebral blood flow in patients with unilateral venous pulsatile tinnitus: an arterial spin labeling study.The British journal of radiology · 2021Article
- Lateralization Effects on Cerebral Blood Flow in Patients With Unilateral Pulsatile Tinnitus Measured With Arterial Spin Labeling.Frontiers in human neuroscience · 2020Article
- Disrupted Intraregional Brain Activity and Functional Connectivity in Unilateral Acute Tinnitus Patients With Hearing Loss.Frontiers in neuroscience · 2019Article
- Tinnitus distress is associated with enhanced resting-state functional connectivity within the default mode network.Neuropsychiatric disease and treatment · 2018Article
- Neuroanatomical Alterations in Patients with Early Stage of Unilateral Pulsatile Tinnitus: A Voxel-Based Morphometry Study.Neural plasticity · 2018Article
- Connectivity of precuneus to the default mode and dorsal attention networks: A possible invariant marker of long-term tinnitus.NeuroImage. Clinical · 2017Article
- Frequency-Dependent Neural Activity in Patients with Unilateral Vascular Pulsatile Tinnitus.Neural plasticity · 2016Article
- Aberrant spontaneous brain activity in chronic tinnitus patients revealed by resting-state functional MRI.NeuroImage. Clinical · 2014Article
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Authors and funding
12 authors.
Funding
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Abstract
Numerous investigations studying the brain functional activity of the tinnitus patients have indicated that neurological changes are important findings of this kind of disease. However, the pulsatile tinnitus (PT) patients were excluded in previous studies because of the totally different mechanisms of the two subtype tinnitus. The aim of this study is to investigate whether altered baseline brain activity presents in patients with PT using resting-state functional magnetic resonance imaging (rs-fMRI) technique. The present study used unilateral PT patients (n = 42) and age-, sex-, and education-matched normal control subjects (n = 42) to investigate the changes in structural and amplitude of low-frequency (ALFF) of the brain. Also, we analyzed the relationships between these changes with clinical data of the PT patients. Compared with normal controls, PT patients did not show any structural changes. PT patients showed significant increased ALFF in the bilateral precuneus, and bilateral inferior frontal gyrus (IFG) and decreased ALFF in multiple occipital areas. Moreover, the increased THI score and PT duration was correlated with increased ALFF in precuneus and bilateral IFG. The abnormalities of spontaneous brain activity reflected by ALFF measurements in the absence of structural changes may provide insights into the neural reorganization in PT patients.
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