ArticleMiddle East journal of digestive diseases2014
The clinical presentation of celiac disease: experiences from northeastern iran.
Article in Middle East journal of digestive diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Prevalence of osteoporosis and osteopenia in men and premenopausal women with celiac disease: a systematic review.Nutrition journal · 2019Pooled it
- Optimal age for screening lumbar osteoporosis in celiac disease.Scientific reports · 2025Article
- Epidemiological, Endoscopic, Clinical, and Pathological Features of Patients with Celiac Diseases in Southern Littoral of Caspian Sea.Middle East journal of digestive diseases · 2023Article
- Clinical profile of patients with seronegative celiac disease.Gastroenterology and hepatology from bed to bench · 2023Article
- Bone Loss Correlated with Parathyroid Hormone Levels in Adult Celiac Patients.Middle East journal of digestive diseases · 2022Article
- Assessment of the Predictive Factors Influencing the Diagnosis and Severity of Villous Atrophy in Patients with Celiac Disease and Iron Deficiency Anemia Referred for Diagnostic Endoscopy in Basrah, Iraq.Medical journal of the Islamic Republic of Iran · 2022Article
- Different Clinical Features of Celiac Disease in Children, Adolescents, and Adults; a Cross-sectional Study.Middle East journal of digestive diseases · 2021Article
- Seronegative Celiac Disease; Frequently Encountered Yet Undiagnosed Clinical Entity.Middle East journal of digestive diseases · 2021Article
- Routine Multiple Duodenal Biopsy during Endoscopy of Dyspeptic Patients Seems Unnecessary for Screening of Celiac Disease.Gastroenterology research and practice · 2020Article
- Adult Celiac Disease: Patients Are Shorter Compared with Their Peers in the General Population.Middle East journal of digestive diseases · 2016Article
- Frequency of Celiac Disease in Patients With Increased Intestinal Gas (Flatulence).Global journal of health science · 2015Article
- Clinical Characteristics of Celiac Disease and Dietary Adherence to Gluten-Free Diet among Saudi Children.Pediatric gastroenterology, hepatology & nutrition · 2015Article
- Assessing of Celiac Disease and Nonceliac Gluten Sensitivity.Gastroenterology research and practice · 2015Review
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND This study aimed to explore demographic characteristics and clinical presentations of celiac disease (CD) in Northeastern Iran. METHODS This was a cross-sectional retrospective study of 193 adults with CD who presented to Mashhad University Gastroenterology Clinic between 2008 and 2013. Patient data that included mode of presentation and the presence of any concomitant illnesses were collected. Intestinal biopsy and serum anti-tissue transglutaminase (anti-tTG) were used for diagnosis. Mucosal lesions were classified according to modified Marsh classification. RESULTS Overall, 132 females and 61 males, with a mean age at diagnosis of 32.6 ± 13.2 years were included. The patient's chief complaints in order of decreasing frequency were dyspepsia (24.6%), diarrhea (20%), anemia (12.8%), and flatulence (7.2%). Bone disease was seen (osteopenia, osteoporosis) in 30% of patients. A positive family history of CD was found in 17.9% of cases. There were 64% who had serum anti-tTG >200 units/ml and 78% had a Marsh classification grade 3 on duodenal biopsy. The histology grade (Marsh) did not show any correlation with anti-tTG serum levels, age, body mass index (BMI) or hemoglobin levels. CONCLUSION In Northeastern Iran, CD was seen more commonly in females and with non-diarrheal presentations. Abdominal discomfort, anemia and bone disease were most common primary presentations in this area. Histology grade showed no significant correlation with level of anti-tTG, BMI or hemoglobin levels. We suggest screening for CD in unexplained abdominal discomfort, bone disease and anemia.
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24872868PMC4034670W2111367521What OpenQuestion holds
Registered trials
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