ArticleInternational journal of nanomedicine2014
Electrospun gelatin/PCL and collagen/PLCL scaffolds for vascular tissue engineering.
Article in International journal of nanomedicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
80 citing papers in PubMed, 263 citations in OpenAlex.
- Application of PLCL as a biodegradable polymer in biomedical engineering.Journal of materials science. Materials in medicine · 2026Review
- Bioengineered Cellular and Acellular Therapies for Ischemic Heart Disease in Clinically Relevant Models.Bioengineering (Basel, Switzerland) · 2026Review
- A bioengineered vinpocetine- and menstrual blood stem cell-loaded neural conduit for treating peripheral nerve injury after bone fractures.Journal of materials science. Materials in medicine · 2025Article
- A 3D Composite Model Using Electrospinning Technology to Study Endothelial Damage.Biomolecules · 2025Article
- Fabrication of Aligned Polyhydroxybutyrate Fibrous Scaffolds via a Touchspinning Apparatus.ACS omega · 2025Article
- Low-cost gelatin/collagen scaffolds for bacterial growth in bioreactors for biotechnology.Applied microbiology and biotechnology · 2025Article
- The Impact of Helium and Nitrogen Plasmas on Electrospun Gelatin Nanofiber Scaffolds for Skin Tissue Engineering Applications.Journal of functional biomaterials · 2024Article
- Fibrin-Polycaprolactone Scaffolds for the Differentiation of Human Neural Progenitor Cells into Dopaminergic Neurons.ACS omega · 2024Article
- Fabrication and biocompatibility evaluation of hydroxyapatite-polycaprolactone-gelatin composite nanofibers as a bone scaffold.RSC advances · 2024Article
- Review
- Article
- Characterization of Gelatin-Polycaprolactone Membranes by Electrospinning.Biomimetics (Basel, Switzerland) · 2024Article
- Ascorbic Acid 2-Phosphate Releasing Supercritically Foamed Porous Poly-L-Lactide-Co-ε-Caprolactone Scaffold Enhances the Collagen Production of Human Vaginal Stromal Cells: A New Approach for Vaginal Tissue Engineering.Tissue engineering and regenerative medicine · 2024Article
- In Vitro Investigation of Gelatin/Polycaprolactone Nanofibers in Modulating Human Gingival Mesenchymal Stromal Cells.Materials (Basel, Switzerland) · 2023Article
- Optimizing PCL/PLGA Scaffold Biocompatibility Using Gelatin from Bovine, Porcine, and Fish Origin.Gels (Basel, Switzerland) · 2023Article
- Vascular endothelial growth factor a modified mRNA engineered cellular electrospun membrane complexes promotes mouse skin wound repair.Materials today. Bio · 2023Article
- From Poly(glycerol itaconate) Gels to Novel Nonwoven Materials for Biomedical Applications.Gels (Basel, Switzerland) · 2023Article
- Antifungal Activity of Camelus-Derived LFA-LFC Chimeric Peptide Gelatin Film and Effect on Oral Bacterial Biofilm.Applied biochemistry and biotechnology · 2023Article
- Fabrication and compatibility evaluation of polycaprolactone/hydroxyapatite/collagen-based fiber scaffold for anterior cruciate ligament injury.RSC advances · 2023Article
- Covalent coating strategy for enhancing the biocompatibility and hemocompatibility of blood-contacting medical materials.Pharmaceutical science advances · 2023Review
20 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Electrospun hybrid nanofibers prepared using combinations of natural and synthetic polymers have been widely investigated in cardiovascular tissue engineering. In this study, electrospun gelatin/polycaprolactone (PCL) and collagen/poly(l-lactic acid-co-ε-caprolactone) (PLCL) scaffolds were successfully produced. Scanning electron micrographs showed that fibers of both membranes were smooth and homogeneous. Water contact angle measurements further demonstrated that both scaffolds were hydrophilic. To determine cell attachment and migration on the scaffolds, both hybrid scaffolds were seeded with human umbilical arterial smooth muscle cells. Scanning electron micrographs and MTT assays showed that the cells grew and proliferated well on both hybrid scaffolds. Gross observation of the transplanted scaffolds revealed that the engineered collagen/PLCL scaffolds were smoother and brighter than the gelatin/PCL scaffolds. Hematoxylin and eosin staining showed that the engineered blood vessels constructed by collagen/PLCL electrospun membranes formed relatively homogenous vessel-like tissues. Interestingly, Young's modulus for the engineered collagen/PLCL scaffolds was greater than for the gelatin/PCL scaffolds. Together, these results indicate that nanofibrous collagen/PLCL membranes with favorable mechanical and biological properties may be a desirable scaffold for vascular tissue engineering.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.