Evidence map›Paper›PMID 24872350›Full record

SynthesisAmerican journal of epidemiology2014

Who is more affected by ozone pollution? A systematic review and meta-analysis.

Michelle L Bell, Antonella Zanobetti, Francesca Dominici

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in American journal of epidemiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michelle L Bell
Antonella Zanobetti
Francesca Dominici

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI SUSAN A KORRICK · 1985 to 2026
$44.6M
Effects of Fine Particle Composition on Birth OutcomesR01ES019587 · NIEHS · YALE UNIVERSITY · PI BELL, MICHELLE L · 2011 to 2015
$2.6M
Statistical Methods for Complex Enivronmental Health DataR01ES019560 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI PENG, ROGER · 2011 to 2015
$1.8M
Air Pollution and Pregnancy Outcome in New York CityR01ES019955 · NIEHS · BROWN UNIVERSITY · PI SAVITZ, DAVID A · 2011 to 2013
$1.3M
Extreme Heat and Human Health: Characterizing Vulnerability in a Changing ClimateR21ES020152 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI PENG, ROGER · 2011 to 2012
$482k
Vulnerability to Health Effects of Wildfires under a Changing Climate in WesternR21ES021427 · NIEHS · YALE UNIVERSITY · PI BELL, MICHELLE L · 2012 to 2013
$466k
Vulnerability and Adaptation to Heat and Air Pollution in a Changing ClimateR21ES022585 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI DOMINICI, FRANCESCA · 2014 to 2015
$454k
NIEHS NIH HHS ES020152NIEHS NIH HHS P30 ES000002NIEHS NIH HHS R01 ES019560NIEHS NIH HHS R01ES019560NIEHS NIH HHS R01 ES019587NIEHS NIH HHS R01ES019587NIEHS NIH HHS R01 ES019955NIEHS NIH HHS R01ES019955NIEHS NIH HHS R21 ES020152NIEHS NIH HHS R21 ES021427NIEHS NIH HHS R21ES021427NIEHS NIH HHS R21 ES022585
6 · The paper itself

Abstract

Ozone is associated with adverse health; however, less is known about vulnerable/sensitive populations, which we refer to as sensitive populations. We systematically reviewed epidemiologic evidence (1988-2013) regarding sensitivity to mortality or hospital admission from short-term ozone exposure. We performed meta-analysis for overall associations by age and sex; assessed publication bias; and qualitatively assessed sensitivity to socioeconomic indicators, race/ethnicity, and air conditioning. The search identified 2,091 unique papers, with 167 meeting inclusion criteria (73 on mortality and 96 on hospitalizations and emergency department visits, including 2 examining both mortality and hospitalizations). The strongest evidence for ozone sensitivity was for age. Per 10-parts per billion increase in daily 8-hour ozone concentration, mortality risk for younger persons, at 0.60% (95% confidence interval (CI): 0.40, 0.80), was statistically lower than that for older persons, at 1.27% (95% CI: 0.76, 1.78). Findings adjusted for publication bias were similar. Limited/suggestive evidence was found for higher associations among women; mortality risks were 0.39% (95% CI: -0.22, 1.00) higher than those for men. We identified strong evidence for higher associations with unemployment or lower occupational status and weak evidence of sensitivity for racial/ethnic minorities and persons with low education, in poverty, or without central air conditioning. Findings show that some populations, especially the elderly, are particularly sensitive to short-term ozone exposure.

Indexed as

Age FactorsAir PollutantsFemaleHospitalizationHumansMaleMortalityOzoneRacial GroupsRisk FactorsSex FactorsSocioeconomic FactorsAir PollutantsOzoneageair pollutioneffect modifiershospitalizationmortalityozonesex

Identifiers

PMID24872350
PMCPMC4070938

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.